C₂₇H₄₂O₇Si

Base Information

• Chemical Name: C₂₇H₄₂O₇Si
• CAS No.: 379692-79-2
• Molecular Formula: C₂₇H₄₂O₇Si
• Molecular Weight: 506.712
• Mol file: 379692-79-2.mol

Synonyms:

Chemical Property of C₂₇H₄₂O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₄₂O₇Si

There total 9 articles about C₂₇H₄₂O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H44O7Si (379692-78-1) → C27H42O7Si (379692-79-2)

Guidance literature:

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; MS 4 Angstroem; In acetonitrile;

DOI:10.1016/S0040-4039(01)01366-1

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → C27H42O7Si (379692-79-2)

Guidance literature:

Multi-step reaction with 5 steps

1: ImH / dimethylformamide / 20 °C

2: OsO₄; NMO / 2-methyl-propan-2-ol; H₂O / 20 °C

3: CSA / CH₂Cl₂ / 20 °C

4: 87 percent / NaOH; DMPU / H₂O / 3 h / 40 °C

5: NMO; TPAP; MS 4 Angstroem / acetonitrile

With 1H-imidazole; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium hydroxide; osmium(VIII) oxide; N-methyl-2-indolinone; tetrapropylammonium perruthennate; MS 4 Angstroem; camphor-10-sulfonic acid; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/S0040-4039(01)01366-1

Reference yield:

(1R,3S,5R,8R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-8-(4-methoxy-benzyloxy)-5-methyl-4-methylene-2-oxa-bicyclo[3.2.1]octan-6-one (379692-75-8) → C27H42O7Si (379692-79-2)

Guidance literature:

Multi-step reaction with 6 steps

1: LiBHEt₃ / tetrahydrofuran / -78 °C

2: ImH / dimethylformamide / 20 °C

3: OsO₄; NMO / 2-methyl-propan-2-ol; H₂O / 20 °C

4: CSA / CH₂Cl₂ / 20 °C

5: 87 percent / NaOH; DMPU / H₂O / 3 h / 40 °C

6: NMO; TPAP; MS 4 Angstroem / acetonitrile

With 1H-imidazole; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium hydroxide; osmium(VIII) oxide; N-methyl-2-indolinone; tetrapropylammonium perruthennate; MS 4 Angstroem; camphor-10-sulfonic acid; lithium triethylborohydride; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1016/S0040-4039(01)01366-1

upstream raw materials:

C₂₇H₄₄O₇Si

tert-butyldimethylsilyl chloride

(1R,3S,5R,8R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-8-(4-methoxy-benzyloxy)-5-methyl-4-methylene-2-oxa-bicyclo[3.2.1]octan-6-one

(1R,3S,5S,6S,8R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-8-(4-methoxy-benzyloxy)-5-methyl-4-methylene-2-oxa-bicyclo[3.2.1]octan-6-ol

Downstream raw materials:

(1R,8R,10R,11R)-10-(tert-Butyl-dimethyl-silanyloxy)-11-(4-methoxy-benzyloxy)-1-methyl-4,7-dioxa-tricyclo[6.2.1.0^2,6]undec-2⁽⁶⁾-en-5-ol