methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Base Information

Chemical Name:methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside
CAS No.:496065-65-7
Molecular Formula:C₂₉H₄₉NO₉Si
Molecular Weight:583.795
Hs Code.:

methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Synonyms:

Suppliers and Price of methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

There total 10 articles about methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87376-50-9
(2R,3R,4R,5R,6R)-5-azido-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4-diol

: 496065-65-7
methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1.1: bis(tributyltin) oxide / toluene / 4.5 h / Heating

1.2: 86 percent / toluene / 2.5 h

2.1: 94 percent / 2,6-di-tert-butyl-4-methylpyridine / CH₂Cl₂ / 4 h / Heating

3.1: 97 percent / sodium methoxide / methanol

4.1: 84 percent / pyridine / 3 h / 20 °C

5.1: molecular sieves 4 Angstroem / CH₂Cl₂ / 1 h

5.2: 71 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / CH₂Cl₂ / 1 h

6.1: 98 percent / sodium methoxide / methanol / 5 h / 0 °C

7.1: DMSO; acetic anhydride / 20 °C

8.1: L-selectride / tetrahydrofuran

9.1: 43 mg / tetrahydrofuran; H₂O

With pyridine; 2,6-di-tert-butyl-4-methylpyridine; 4 A molecular sieve; sodium methylate; acetic anhydride; L-Selectride; dimethyl sulfoxide; bis(tri-n-butyltin)oxide; In tetrahydrofuran; methanol; dichloromethane; water; toluene; 3.1: Zemplen transesterification / 6.1: Zemplen transesterification;
DOI:10.1139/v02-117

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 496065-65-7
methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: 84 percent / pyridine / 3 h / 20 °C

2.1: molecular sieves 4 Angstroem / CH₂Cl₂ / 1 h

2.2: 71 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / CH₂Cl₂ / 1 h

3.1: 98 percent / sodium methoxide / methanol / 5 h / 0 °C

4.1: DMSO; acetic anhydride / 20 °C

5.1: L-selectride / tetrahydrofuran

6.1: 43 mg / tetrahydrofuran; H₂O

With pyridine; 4 A molecular sieve; sodium methylate; acetic anhydride; L-Selectride; dimethyl sulfoxide; In tetrahydrofuran; methanol; dichloromethane; water; 3.1: Zemplen transesterification;
DOI:10.1139/v02-117

Reference yield:

: 496065-62-4
methyl 2-azido-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

: 496065-65-7
methyl 2-acetamido-3-O-(4-O-benzyl-3,6-dideoxy-β-D-arabino-hexopyranosyl)-6-O-tert-butyldimethylsilyl-2-deoxy-4-O-methyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: molecular sieves 4 Angstroem / CH₂Cl₂ / 1 h

1.2: 71 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / CH₂Cl₂ / 1 h

2.1: 98 percent / sodium methoxide / methanol / 5 h / 0 °C

3.1: DMSO; acetic anhydride / 20 °C

4.1: L-selectride / tetrahydrofuran

5.1: 43 mg / tetrahydrofuran; H₂O

With 4 A molecular sieve; sodium methylate; acetic anhydride; L-Selectride; dimethyl sulfoxide; In tetrahydrofuran; methanol; dichloromethane; water; 2.1: Zemplen transesterification;
DOI:10.1139/v02-117