C₂₄H₂₇NO₂

Base Information

• Chemical Name: C₂₄H₂₇NO₂
• CAS No.: 1565829-53-9
• Molecular Formula: C₂₄H₂₇NO₂
• Molecular Weight: 361.484
• Mol file: 1565829-53-9.mol

Synonyms:

Chemical Property of C₂₄H₂₇NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₇NO₂

There total 9 articles about C₂₄H₂₇NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

C24H28BrNO2 (1565829-21-1) → C24H27NO2 + C24H27NO2 (1565829-53-9) + C24H27NO2 (1565829-55-1)

Guidance literature:

With sodium amide; In tetrahydrofuran; tert-butyl alcohol; at 23 ℃; for 3h; enantiospecific reaction; Inert atmosphere;

DOI:10.1021/ja501142e

Reference yield:

2-hydroxycarbazole (86-79-3) → C24H27NO2 + C24H27NO2 (1565829-53-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: N-Bromosuccinimide / tetrahydrofuran / 0.17 h / 23 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0.42 h / 0 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C / Inert atmosphere

3.2: 0.33 h / Inert atmosphere

4.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / -78 - 23 °C / Inert atmosphere

4.2: 24 h / 65 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 23 °C / Inert atmosphere

6.1: sodium amide / tetrahydrofuran; tert-butyl alcohol / 3 h / 23 °C / Inert atmosphere

With N-Bromosuccinimide; tetrabutyl ammonium fluoride; sodium hydride; sodium amide; triethylamine; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; dichloromethane; mineral oil; tert-butyl alcohol;

DOI:10.1021/ja501142e

Reference yield:

C10H16O → C24H27NO2 + C24H27NO2 (1565829-53-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrahydrofuran / -78 - 23 °C / Inert atmosphere

2.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / -78 - 23 °C / Inert atmosphere

2.2: 24 h / 65 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 23 °C / Inert atmosphere

4.1: sodium amide / tetrahydrofuran; tert-butyl alcohol / 3 h / 23 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; sodium amide; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; tert-butyl alcohol;

DOI:10.1021/ja501142e

upstream raw materials:

2-hydroxycarbazole

C₁₃H₇BrF₃NO₃S

C₁₅H₁₁BrF₃NO₄S

(R)-(+)-3,4-dimethyl-2-cyclohexen-1-one