C₁₈H₁₇N₃O

Base Information

• Chemical Name: C₁₈H₁₇N₃O
• CAS No.: 1374747-16-6
• Molecular Formula: C₁₈H₁₇N₃O
• Molecular Weight: 291.352
• Mol file: 1374747-16-6.mol

Synonyms:

Chemical Property of C₁₈H₁₇N₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₇N₃O

There total 4 articles about C₁₈H₁₇N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H18IN3O → C18H17N3O (1374747-16-6)

Guidance literature:

With lithium tert-butoxide; In N,N-dimethyl-formamide; at 140 ℃; for 4h; Inert atmosphere;

DOI:10.1002/ejoc.201101816

Reference yield:

iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene (1374746-75-4) → C18H17N3O (1374747-16-6)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide; N,N,N,N,-tetramethylethylenediamine / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2: lithium tert-butoxide / N,N-dimethyl-formamide / 4 h / 140 °C / Inert atmosphere

With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; lithium tert-butoxide; In N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201101816

Reference yield:

1-iodo-3,5-dimethyl-4-hydroxybenzene (90003-93-3) → C18H17N3O (1374747-16-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide; toluene / 12 h / 20 °C / Inert atmosphere

2: copper(l) iodide; N,N,N,N,-tetramethylethylenediamine / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

3: lithium tert-butoxide / N,N-dimethyl-formamide / 4 h / 140 °C / Inert atmosphere

With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; potassium carbonate; lithium tert-butoxide; In N,N-dimethyl-formamide; toluene;

DOI:10.1002/ejoc.201101816

upstream raw materials:

iodo-3,5-dimethyl-2-(prop-2-yn-1-yloxy)benzene

1-iodo-3,5-dimethyl-4-hydroxybenzene

2,4-Xylenol