C₁₅H₂₁NO₄

Base Information

• Chemical Name: C₁₅H₂₁NO₄
• CAS No.: 1217456-02-4
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.336
• Mol file: 1217456-02-4.mol

Synonyms:

Chemical Property of C₁₅H₂₁NO₄

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2R, 3R)-3-(Boc-amino)-2-methyl-3-phenylpropionic acid ≥90.0% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₂₁NO₄

There total 10 articles about C₁₅H₂₁NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

((1S,2S)-2-methyl-3-oxo-1-phenylpropyl)carbamic acid tert-butyl ester (926308-17-0) → C15H21NO4 (926308-22-7,1217456-02-4)

Guidance literature:

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene;

DOI:10.1002/anie.200603188

Reference yield:

tert-butyl benzylidenecarbamate (177896-09-2) → C15H21NO4 (926308-22-7,1217456-02-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / (S)-proline / dimethylformamide / 16 h / 4 °C

2: 68 percent / NaClO₂; iso-butene; KH₂PO₄ / CHCl₃; 2-methyl-propan-2-ol; H₂O / 16 h / 20 °C

With sodium chlorite; potassium dihydrogenphosphate; L-proline; In chloroform; water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1016/j.tetlet.2006.11.076

Reference yield:

tert-butyl (1S,2R)-2-methyl-3-oxo-1-phenylpropylcarbamate (946152-70-1) → C15H21NO4 (1217456-02-4)

Guidance literature:

With sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; for 4h;

DOI:10.1002/anie.200805628

upstream raw materials:

((1S,2S)-2-methyl-3-oxo-1-phenylpropyl)carbamic acid tert-butyl ester

tert-butyl benzylidenecarbamate

tert-butyl (1S,2R)-2-methyl-3-oxo-1-phenylpropylcarbamate

benzonitrile