C₁₆H₂₁NO₈

Base Information

Chemical Name:C₁₆H₂₁NO₈
CAS No.:1609382-19-5
Molecular Formula:C₁₆H₂₁NO₈
Molecular Weight:355.345
Hs Code.:

C<sub>16</sub>H<sub>21</sub>NO<sub>8</sub>

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₂₁NO₈

Chemical Property:

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Technology Process of C₁₆H₂₁NO₈

There total 2 articles about C₁₆H₂₁NO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57-04-5
dihydroxyacetone phosphate

: N-Cbz-(2R,3S,4S)-3,4-dihydroxypyrrolidine-2-carbaldehyde

: 1609382-19-5
C₁₆H₂₁NO₈

Guidance literature:: dihydroxyacetone phosphate; N-Cbz-(2R,3S,4S)-3,4-dihydroxypyrrolidine-2-carbaldehyde; With L-fuculose-1-phosphate aldolase F₁₃₁A variant; potassium chloride; In N,N-dimethyl-formamide; at 0 - 4 ℃; for 24h; pH=6.7 - 6.9; Enzymatic reaction;

With acid phosphatase; for 24h; pH=5; stereoselective reaction; Enzymatic reaction;
DOI:10.1021/jo500991p

Reference yield:

: 67561-03-9
N-benzyloxycarbonylglycinal

: 1609382-19-5
C₁₆H₂₁NO₈

Guidance literature:: Multi-step reaction with 3 steps

1.1: Enzymatic reaction

1.2: 2585.81 Torr

2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / Reflux

3.1: potassium chloride; L-fuculose-1-phosphate aldolase F₁₃₁A variant / N,N-dimethyl-formamide / 24 h / 0 - 4 °C / pH 6.7 - 6.9 / Enzymatic reaction

3.2: 3407 / 24 h / pH 5 / Enzymatic reaction

With L-fuculose-1-phosphate aldolase F₁₃₁A variant; potassium chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In ethyl acetate; N,N-dimethyl-formamide; 3.1: |Aldol Addition;
DOI:10.1021/jo500991p