diphenylmethyl 11-deoxo-18β-glycyrrhetinate

Base Information

• Chemical Name: diphenylmethyl 11-deoxo-18β-glycyrrhetinate
• CAS No.: 441759-68-8
• Molecular Formula: C₄₃H₅₈O₃
• Molecular Weight: 622.932
• Mol file: 441759-68-8.mol

Synonyms:

Chemical Property of diphenylmethyl 11-deoxo-18β-glycyrrhetinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenylmethyl 11-deoxo-18β-glycyrrhetinate

There total 2 articles about diphenylmethyl 11-deoxo-18β-glycyrrhetinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

enoxolone (471-53-4) → diphenylmethyl 11-deoxo-18β-glycyrrhetinate (441759-68-8)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pt

With hydrogen; platinum;

DOI:10.1007/s706-002-8243-6

Reference yield:

11-deoxyglycyrrhetinic acid (6894-46-8,14796-53-3,17956-00-2,76035-62-6,564-16-9) + diazodiphenylmethane (908093-98-1) → diphenylmethyl 11-deoxo-18β-glycyrrhetinate (441759-68-8)

Guidance literature:

DOI:10.1007/s706-002-8243-6

Reference yield: 56.6%

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) + diphenylmethyl 11-deoxo-18β-glycyrrhetinate (441759-68-8) → diphenylmethyl 2',3',6',2'',3'',4'',6''-heptaacetyl-β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-11-deoxy-18β-glycyrrhetinate (441759-71-3)

Guidance literature:

With mercury(II) cyanide; In nitromethane; benzene; for 4h; Heating;

DOI:10.1007/s706-002-8243-6

upstream raw materials:

11-deoxyglycyrrhetinic acid

diazodiphenylmethane

enoxolone

Downstream raw materials:

diphenylmethyl 2',3',6',2'',3'',4'',6''-heptaacetyl-β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-11-deoxy-18β-glycyrrhetinate

Refernces