pentane-1,5-diyl bis(4-nitrobenzoate)

Base Information

• Chemical Name: pentane-1,5-diyl bis(4-nitrobenzoate)
• CAS No.: 22104-39-8
• Molecular Formula: C19H18 N2 O8
• Molecular Weight: 402.361
• Mol file: 22104-39-8.mol

Synonyms:1,5-Pentanediol,bis(4-nitrobenzoate) (9CI); 1,5-Pentanediol, bis(p-nitrobenzoate) (8CI);1,5-Pentanediol di-p-nitrobenzoate; NSC 94648

Chemical Property of pentane-1,5-diyl bis(4-nitrobenzoate)

Chemical Property:

• Vapor Pressure: 3.26E-13mmHg at 25°C
• Boiling Point: 574.7°C at 760 mmHg
• Flash Point: 232°C
• Density: 1.344g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of pentane-1,5-diyl bis(4-nitrobenzoate)

There total 4 articles about pentane-1,5-diyl bis(4-nitrobenzoate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1 ,5-pentanediol (111-29-5) + 4-nitro-benzoyl chloride (122-04-3) → pentane-1,5-diyl bis-(p-nitrobenzoate) (22104-39-8)

Guidance literature:

With triethylamine; In toluene; at 10 ℃; for 3.25h; Reflux;

DOI:10.1016/j.jorganchem.2013.08.002

Reference yield:

1 ,5-pentanediol (111-29-5) + 4-nitro-benzoic acid (62-23-7) → pentane-1,5-diyl bis-(p-nitrobenzoate) (22104-39-8)

Guidance literature:

With benzenesulfonic acid; In water; toluene; Reflux;

Reference yield:

3,4,5,6-tetrahydro-2H-pyran-2-one (542-28-9,26354-94-9) → pentane-1,5-diyl bis-(p-nitrobenzoate) (22104-39-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ZnCl₂ / 120 - 130 °C

With zinc(II) chloride;

upstream raw materials:

1 ,5-pentanediol

4-nitro-benzoyl chloride

1,5-Bis-triaethylsilyloxy-pentan

3,4,5,6-tetrahydro-2H-pyran-2-one

Downstream raw materials:

1 ,5-pentanediol

1,5-bis(4-aminobenzoyloxy)pentane

Refernces

• 1、 -. "Preparation method of cis-atracurium besylate". Paragraph 0045-0049. . Retrieved 2020/12/29.
• 2、 Battersby, Alan R.,Murphy, Roger,Staunton, James. "Studies of Enzyme-mediated Reactions. Part 14. Stereochemical Course of the Formation of Cadaverine by Decarboxylation of (2S)-Lysine with Lysine Decarboxylase (E.C.4.1.1.18) from Bacillus cadaveris". . p. 449 - 453. Retrieved 2007/10/02.