5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Base Information

Chemical Name:5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS No.:139713-57-8
Molecular Formula:C7H5ClN2O2
Molecular Weight:184.58000
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60350659
Mol file:139713-57-8.mol

Synonyms:139713-57-8;5-chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile;5-chloro-6-hydroxy-4-methyl-2-oxo-1H-pyridine-3-carbonitrile;DTXSID60350659;STK674710;AKOS001740327;SR-01000521543;5-chloro-3-cyano-6-hydroxy-4-methylpyridin-2-one;SR-01000521543-1

Suppliers and Price of 5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 95+%
10g
$ 2084.00

Crysdot
5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 95+%
5g
$ 1538.00

Crysdot
5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 95+%
1g
$ 842.00

American Custom Chemicals Corporation
3-CYANO-4-METHYL-5-CHLORO-6-HYDROXY-2-PYRIDONE 95.00%
5MG
$ 498.62

Total 5 raw suppliers

Chemical Property of 5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Chemical Property:

PSA：76.88000
LogP:0.91398
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:184.0039551
Heavy Atom Count:12
Complexity:359

Purity/Quality:

98% ^*data from raw suppliers

5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)NC(=C1Cl)O)C#N

Technology Process of 5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

There total 1 articles about 5-Chloro-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 5444-02-0
3-cyano-4-methyl-6-hydroxypyrid-2-one

: 139713-57-8
5-chloro-3-cyano-6-hydroxy-4-methylpyrid-2-one

Guidance literature:: 3-cyano-4-methyl-6-hydroxypyrid-2-one; With chlorine; In tetrachloromethane; at 20 - 25 ℃;

With zinc; In ethanol; at 30 ℃;
DOI:10.1007/BF02251818

Reference yield: 69.0%

: 139713-57-8
5-chloro-3-cyano-6-hydroxy-4-methylpyrid-2-one

: 63195-39-1
3-Cyano-2,5,6-trichlor-4-methylpyridin

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1023/B:COHC.0000028626.45566.67

Reference yield:

: 139713-57-8
5-chloro-3-cyano-6-hydroxy-4-methylpyrid-2-one

: 2,5,6-trichloro-4-methyl-nicotinic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / POCl₃ / Heating

2: 69 percent / aq. H₂SO₄ / Heating

3: 75 percent / H₂SO₄; aq. NaNO₂

With sulfuric acid; sodium nitrite; trichlorophosphate;
DOI:10.1023/B:COHC.0000028626.45566.67