2-bromo-3-phenylpropyl benzyl(phenyl)carbamate

Base Information

• Chemical Name: 2-bromo-3-phenylpropyl benzyl(phenyl)carbamate
• CAS No.: 1239921-44-8
• Molecular Formula: C₂₃H₂₂BrNO₂
• Molecular Weight: 424.337
• Mol file: 1239921-44-8.mol

Synonyms:

Chemical Property of 2-bromo-3-phenylpropyl benzyl(phenyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-3-phenylpropyl benzyl(phenyl)carbamate

There total 1 articles about 2-bromo-3-phenylpropyl benzyl(phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 2-bromo-3-phenylpropan-1-ol (66820-58-4) + N-Benzylaniline (758640-21-0,103-32-2) → 2-bromo-3-phenylpropyl benzyl(phenyl)carbamate (1239921-44-8)

Guidance literature:

bis(trichloromethyl) carbonate; 2-bromo-3-phenylpropan-1-ol; With 2,6-dimethylpyridine; In diethyl ether; at -78 - 20 ℃; Inert atmosphere;

N-Benzylaniline; With 2,6-dimethylpyridine; In diethyl ether; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja105924f

Reference yield:

2-bromo-3-phenylpropyl benzyl(phenyl)carbamate (1239921-44-8) + 9-hexyl-9-borabicyclo[3.3.1]nonane (42371-64-2) → 2-benzyloctyl benzyl(phenyl)carbamate

Guidance literature:

9-hexyl-9-borabicyclo[3.3.1]nonane; With potassium tert-butylate; hexan-1-ol; In di-isopropyl ether; for 0.75h; Inert atmosphere;

2-bromo-3-phenylpropyl benzyl(phenyl)carbamate; With diethylene glycol dimethyl ether; (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine; In di-isopropyl ether; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja105924f

Reference yield:

2-bromo-3-phenylpropyl benzyl(phenyl)carbamate (1239921-44-8) + 9-hexyl-9-borabicyclo[3.3.1]nonane (42371-64-2) → 2-benzyloctyl benzyl(phenyl)carbamate

Guidance literature:

9-hexyl-9-borabicyclo[3.3.1]nonane; With potassium tert-butylate; hexan-1-ol; In di-isopropyl ether; for 0.75h; Inert atmosphere;

2-bromo-3-phenylpropyl benzyl(phenyl)carbamate; With diethylene glycol dimethyl ether; (1R,2R)-(+)-N,N'-dimethyl-1,2-diphenyl-ethylenediamine; In di-isopropyl ether; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja105924f

upstream raw materials:

bis(trichloromethyl) carbonate

2-bromo-3-phenylpropan-1-ol

N-Benzylaniline

Refernces