Technology Process of trans-3-phenyl-4-<(E)-styryl>-1-cyclohexene
There total 5 articles about trans-3-phenyl-4-<(E)-styryl>-1-cyclohexene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 0 - 20 °C
2.1: acetonitrile / Reflux
3.1: n-butyllithium / toluene; hexane / 0.5 h / -20 °C
3.2: 3 h / Reflux
With
sodium tetrahydroborate; n-butyllithium;
In
methanol; hexane; toluene; acetonitrile;
3.1: |Schlosser Modification / 3.2: |Schlosser Modification;
DOI:10.1002/bkcs.10321
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: boron trifluoride diethyl etherate / dichloromethane / 1 h / -78 °C
2.1: n-butyllithium / toluene; hexane / 0.5 h / -20 °C
2.2: 3 h / Reflux
With
n-butyllithium; boron trifluoride diethyl etherate;
In
hexane; dichloromethane; toluene;
1.1: |Diels-Alder Cycloaddition / 2.1: |Schlosser Modification / 2.2: |Schlosser Modification;
DOI:10.1002/bkcs.10321
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetonitrile / Reflux
2.1: n-butyllithium / toluene; hexane / 0.5 h / -20 °C
2.2: 3 h / Reflux
With
n-butyllithium;
In
hexane; toluene; acetonitrile;
2.1: |Schlosser Modification / 2.2: |Schlosser Modification;
DOI:10.1002/bkcs.10321
