5-nitro-2-phenylsulfanyl-benzoic acid

Base Information

• Chemical Name: 5-nitro-2-phenylsulfanyl-benzoic acid
• CAS No.: 6345-67-1
• Molecular Formula: C13H9 N O4 S
• Molecular Weight: 275.285
• Hs Code.: 2930909090
• Mol file: 6345-67-1.mol

Synonyms:2-(Phenylthio)-5-nitrobenzoicacid; 5-Nitro-2-(phenylthio)benzoic acid; NSC 43574

Chemical Property of 5-nitro-2-phenylsulfanyl-benzoic acid

Chemical Property:

• Vapor Pressure: 1.9E-09mmHg at 25°C
• Boiling Point: 465°C at 760 mmHg
• Flash Point: 235°C
• PSA: 108.42000
• Density: 1.47g/cm³
• LogP: 3.96740

Purity/Quality:

5-Nitro-2-(phenylthio)benzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-nitro-2-phenylsulfanyl-benzoic acid

There total 6 articles about 5-nitro-2-phenylsulfanyl-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

thiophenol (108-98-5) + 2-bromo-5-nitrobenzoic acid (943-14-6) → 2-carboxy-4-nitrodiphenyl sulphide (6345-67-1)

Guidance literature:

With copper(I) oxide; copper; potassium carbonate; In 2-ethoxy-ethanol; at 130 ℃; for 4h;

DOI:10.1055/s-2007-990875

Reference yield: 87.0%

2-chloro-5-nitrobenzoic acid (2516-96-3) + thiophenol (108-98-5) → 2-carboxy-4-nitrodiphenyl sulphide (6345-67-1)

Guidance literature:

With potassium carbonate; In water; at 150 ℃; for 2h;

DOI:10.3184/174751912X13524831206251

Reference yield: 87.0%

2-fluoro-5-nitrobenzoic acid (7304-32-7) + thiophenol (108-98-5) → 2-carboxy-4-nitrodiphenyl sulphide (6345-67-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 20h; Heating;

DOI:10.1021/jm030233b

upstream raw materials:

2-chloro-5-nitrobenzoic acid

thiophenol

2-iodo-5-nitro-benzoic acid

2-fluoro-5-nitrobenzoic acid

Downstream raw materials:

3-nitro-6-(phenylthio)-benzyl alcohol

2,3-Bis(5-nitro-2-phenylthiophenyl)propionitril

5-(Acetamido)-2-(phenylthio)phenylacetonitril

5-(Acetamido)-2-(phenylthio)benzylchlorid