Tyr D_.Met Gly Phe Met NH₂

Base Information

• Chemical Name: Tyr D_.Met Gly Phe Met NH₂
• CAS No.: 74095-40-2
• Molecular Formula: C₃₀H₄₂N₆O₆S₂
• Molecular Weight: 646.832
• Mol file: 74095-40-2.mol

Synonyms:

Chemical Property of Tyr D_.Met Gly Phe Met NH₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tyr D_.Met Gly Phe Met NH₂

There total 10 articles about Tyr D_.Met Gly Phe Met NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc Tyr D.Met Gly Phe Met NH2 (117747-82-7) → Tyr D.Met Gly Phe Met NH2 (74095-40-2)

Guidance literature:

With hydrogenchloride; acetic acid; In various solvent(s);

Reference yield:

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → Tyr D.Met Gly Phe Met NH2 (74095-40-2)

Guidance literature:

Multi-step reaction with 5 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

2: HCl /acetic acid/ anisole / 1.5 h

3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

4: NH₃ / methanol

5: HCl, acetic acid / various solvent(s)

With hydrogenchloride; ammonia; benzotriazol-1-ol; acetic acid; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;

Reference yield:

Methyl ester of N-t-butyloxycarbonyl-L-phenylalanyl-L-methionine (40290-63-9) → Tyr D.Met Gly Phe Met NH2 (74095-40-2)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl /acetic acid/ anisole / 1.5 h

2: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

3: NH₃ / methanol

4: HCl, acetic acid / various solvent(s)

With hydrogenchloride; ammonia; benzotriazol-1-ol; acetic acid; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;

upstream raw materials:

Boc Tyr D_.Met Gly Phe Met NH₂

N-tert-butoxycarbonyl-L-phenylalanine

Methyl ester of N-t-butyloxycarbonyl-L-phenylalanyl-L-methionine

L-phenylalanyl-L-methionine methyl ester

Refernces