C₆₆H₇₆N₄O₁₆

Base Information

• Chemical Name: C₆₆H₇₆N₄O₁₆
• CAS No.: 207917-30-4
• Molecular Formula: C₆₆H₇₆N₄O₁₆
• Molecular Weight: 1181.35
• Mol file: 207917-30-4.mol

Synonyms:

Chemical Property of C₆₆H₇₆N₄O₁₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₇₆N₄O₁₆

There total 14 articles about C₆₆H₇₆N₄O₁₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + C64H74N4O15 → C66H76N4O16 (207917-30-4)

Guidance literature:

With dmap; In pyridine; at 20 ℃; for 24h; Yield given;

DOI:10.1007/bf02495661

Reference yield:

6-deoxy-L-galactose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) → C66H76N4O16 (207917-30-4)

Guidance literature:

Multi-step reaction with 9 steps

1: 1.) Ac₂O, AcONa, 2.) Et₂O*BF₃, 3.) MeONa / 1.) 100 deg C, 2.) CH₂Cl₂, 8 h, 3.) MeOH, 20 deg C, 16 h

2: TsOH*H₂O / 24 h / 20 °C

3: KOH / dimethylsulfoxide / 0.5 h / 30 - 40 °C

4: 90percent aq. CF₃COOH / CHCl₃ / 0.25 h / 20 °C

5: 1.) Bu₂SnO, 2.) Et₄NBr / 1.) benzene, reflux, 2.) reflux

6: 95 percent / pyridine

7: 73 percent / Bu₄NBr, 4 Angstroem MS, CuBr₂ / CH₂Cl₂ / 72 h / 20 °C

8: N₂H₄*H₂O / propan-1-ol / 8 h / Heating

9: DMAP / pyridine / 24 h / 20 °C

With dmap; potassium hydroxide; 4 Angstroem MS; boron trifluoride diethyl etherate; tetraethylammonium bromide; tetrabutylammomium bromide; sodium methylate; sodium acetate; acetic anhydride; di(n-butyl)tin oxide; toluene-4-sulfonic acid; hydrazine hydrate; trifluoroacetic acid; copper(ll) bromide; In pyridine; propan-1-ol; dichloromethane; chloroform; dimethyl sulfoxide;

DOI:10.1007/bf02495661

Reference yield:

benzyl 3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (80035-35-4) → C66H76N4O16 (207917-30-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 86 percent / Et₃N, DMAP / dimethylformamide / 0.5 h / 20 °C

2: 4 Angstroem MS, BF₃*Et₂O / acetonitrile; CH₂Cl₂ / 1 h / -40 °C

3: TsOH*H₂O / acetonitrile / 1 h / 50 °C

4: 73 percent / Bu₄NBr, 4 Angstroem MS, CuBr₂ / CH₂Cl₂ / 72 h / 20 °C

5: N₂H₄*H₂O / propan-1-ol / 8 h / Heating

6: DMAP / pyridine / 24 h / 20 °C

With dmap; 4 Angstroem MS; boron trifluoride diethyl etherate; tetrabutylammomium bromide; toluene-4-sulfonic acid; hydrazine hydrate; triethylamine; copper(ll) bromide; In pyridine; propan-1-ol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1007/bf02495661

upstream raw materials:

acetic anhydride

6-deoxy-L-galactose

benzyl 3-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

ethyl 1-thio-α-L-fucopyranoside