6-n-heptylcyclohex-1-enecarboxylic acid

Base Information

• Chemical Name: 6-n-heptylcyclohex-1-enecarboxylic acid
• CAS No.: 73980-91-3
• Molecular Formula: C₁₄H₂₄O₂
• Molecular Weight: 224.343
• Mol file: 73980-91-3.mol

Synonyms:

Chemical Property of 6-n-heptylcyclohex-1-enecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-n-heptylcyclohex-1-enecarboxylic acid

There total 3 articles about 6-n-heptylcyclohex-1-enecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-n-heptylcyclohex-1-enecarbonitrile (73978-31-1) → 6-n-heptylcyclohex-1-enecarboxylic acid (73980-91-3)

Guidance literature:

With sulfuric acid; sodium nitrite; Yield given. Multistep reaction; 1) acetic acid, 110 deg C, 18 h; 2) water, acetic acid, room temperature (20 min), 80 deg C (1.5 h);

DOI:10.1002/jps.2600690221

Reference yield:

2-heptylcyclohexanone (3313-59-5) → 6-n-heptylcyclohex-1-enecarboxylic acid (73980-91-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 15 g / Et₃N / 2 h / Ambient temperature

2: 1.6 g / thionyl chloride, pyridine / 1 h / 140 °C

3: 1.) H₂SO₄, 2.) sodium nitrite / 1) acetic acid, 110 deg C, 18 h; 2) water, acetic acid, room temperature (20 min), 80 deg C (1.5 h)

With pyridine; thionyl chloride; sulfuric acid; triethylamine; sodium nitrite;

DOI:10.1002/jps.2600690221

Reference yield:

(2-heptyl-1-hydroxycyclohexyl)carbonitrile (73978-29-7) → 6-n-heptylcyclohex-1-enecarboxylic acid (73980-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.6 g / thionyl chloride, pyridine / 1 h / 140 °C

2: 1.) H₂SO₄, 2.) sodium nitrite / 1) acetic acid, 110 deg C, 18 h; 2) water, acetic acid, room temperature (20 min), 80 deg C (1.5 h)

With pyridine; thionyl chloride; sulfuric acid; sodium nitrite;

DOI:10.1002/jps.2600690221

upstream raw materials:

6-n-heptylcyclohex-1-enecarbonitrile

2-heptylcyclohexanone

(2-heptyl-1-hydroxycyclohexyl)carbonitrile