{[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane

Base Information

Chemical Name:{[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane
CAS No.:139765-97-2
Molecular Formula:C16H28O3SSi
Molecular Weight:328.548
Hs Code.:
DSSTox Substance ID:DTXSID20570972
Mol file:139765-97-2.mol

Synonyms:139765-97-2;DTXSID20570972;{[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane

Suppliers and Price of {[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of {[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:328.15284246
Heavy Atom Count:21
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCS(=O)(=O)C1=CC=CC=C1)O[Si](C)(C)C(C)(C)C

Technology Process of {[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane

There total 3 articles about {[4-(Benzenesulfonyl)butan-2-yl]oxy}(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 3112-85-4
methylphenylsulfonate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 75-56-9,16033-71-9
methyloxirane

: 139765-97-2
3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)butane

Guidance literature:: methylphenylsulfonate; methyloxirane; With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; In tetrahydrofuran; hexane; at 25 ℃; for 0.25h;

tert-butyldimethylsilyl chloride; With triethylamine; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/S0040-4020(99)00832-7

Reference yield:

: 65288-08-6
(RS)-4-phenylsulfonyl-2-butanol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 139765-97-2
3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)butane

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; Yield given;
DOI:10.1016/S0040-4039(00)92345-1

Reference yield:

: 3112-85-4
methylphenylsulfonate

: 139765-97-2
3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)butane

Guidance literature:: Multi-step reaction with 2 steps

1: 1) n-BuLi, 2) DMPU / 1) THF, -78 deg C, 2) RT

2: NEt₃ / tetrahydrofuran / 0 °C

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; triethylamine; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)92345-1