syn-1-cyclohexyl-1-hydroxy-2-methyl-3-pentanone

Base Information

• Chemical Name: syn-1-cyclohexyl-1-hydroxy-2-methyl-3-pentanone
• CAS No.: 100483-71-4
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• Mol file: 100483-71-4.mol

Synonyms:

Chemical Property of syn-1-cyclohexyl-1-hydroxy-2-methyl-3-pentanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of syn-1-cyclohexyl-1-hydroxy-2-methyl-3-pentanone

There total 27 articles about syn-1-cyclohexyl-1-hydroxy-2-methyl-3-pentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(4R,5R)-4-Cyclohexyl-6-eth-(Z)-ylidene-5-methyl-[1,3]dioxan-2-one → anti-1-hydroxy-2-methyl-1-cyclohexyl-3-pentanone (81640-09-7,81640-10-0,100483-71-4)

Guidance literature:

With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; Ambient temperature;

DOI:10.1021/jo990439d

Reference yield: 82.0%

(4R,5R)-5-Cyclohexyl-3-eth-(E)-ylidene-2,2,4-trimethyl-[1,2]oxasilolane → anti-1-hydroxy-2-methyl-1-cyclohexyl-3-pentanone (81640-09-7,81640-10-0,100483-71-4)

Guidance literature:

With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate; In tetrahydrofuran; methanol; water; for 3.5h;

DOI:10.1021/ol0061182

Reference yield: 77.0%

pentan-3-one (96-22-0) + cyclohexanecarbaldehyde (2043-61-0) → anti-1-hydroxy-2-methyl-1-cyclohexyl-3-pentanone (81640-09-7,81640-10-0,100483-71-4)

Guidance literature:

With titanium(IV) isopropylate; phenylmagnesium bromide; In toluene; for 8h; Ambient temperature;

DOI:10.1016/0040-4020(95)00496-U

upstream raw materials:

3-pentanone lithium enolate

cyclohexanecarbaldehyde

pentan-3-one

9-((Z)-1-Ethyl-propenyloxy)-9-bora-bicyclo[3.3.1]nonane

Downstream raw materials:

(1S,2R,3S)-1-cyclohexyl-3-hydroxy-2-methylpentyl cyclohexanecarboxylate

(1S,2S,3S)-1-cyclohexyl-3-hydroxy-2-methylpentyl cyclohexanecarboxylate

(1R,2R,3R)-1-cyclohexyl-3-hydroxy-2-methylpentyl cyclohexanecarboxylate

(1R,2S,3R)-1-cyclohexyl-3-hydroxy-2-methylpentyl cyclohexanecarboxylate