3-ethylcyclohexanone

Base Information

• Chemical Name: 3-ethylcyclohexanone
• CAS No.: 64847-85-4
• Molecular Formula: C₈H₁₄O
• Molecular Weight: 126.199
• Mol file: 64847-85-4.mol

Synonyms:

Chemical Property of 3-ethylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ethylcyclohexanone

There total 113 articles about 3-ethylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexenone (930-68-7) + diethylzinc (557-20-0) → 3-ethylcyclohexanone (22461-89-8,64847-85-4,74006-74-9,74006-73-8)

Guidance literature:

With copper(I) thiophene-2-carboxylate; chiral biphenol P-N ligand; In diethyl ether;

DOI:10.1021/ja025598k

Reference yield: 100.0%

cyclohexenone (930-68-7) + diethylzinc (557-20-0) → (R)-3-ethylcyclohexanone (22461-89-8,64847-85-4,74006-73-8,74006-74-9)

Guidance literature:

With copper(I) thiophene-2-carboxylate; chiral binapthol P-N ligand; In diethyl ether;

DOI:10.1021/ja025598k

Reference yield: 100.0%

cyclohexenone (930-68-7) + diethylzinc (557-20-0) → 3-ethyl cyclohexanone (64847-85-4,74006-73-8,74006-74-9,22461-89-8)

Guidance literature:

With copper(l) iodide; C₁₉H₁₉N₂O₂P; In dichloromethane; at -20 ℃; for 12h;

DOI:10.1016/S0957-4166(01)00220-8

upstream raw materials:

cyclohexenone

ethylmagnesium bromide

3-ethylcyclohex-2-en-1-one

ethylmagnesium iodide

Downstream raw materials:

(3-ethylphenyl)phenylmethane

(R)-3-ethylcyclohexanone

3-ethylcyclohexanone

(1S,3R)-3-ethyl-cyclohexanol

Refernces

• 1、 Lewis, William,Nouch, Ryan,Robinson, David,Willcox, Darren,Woodward, Simon. "Mechanistic-Insight-Driven Rate Enhancement of Asymmetric Copper-Catalyzed 1,4-Addition of Dialkylzinc Reagents to Enones". supporting information. . Retrieved 2020/03/13.
• 2、 Brüllingen, Eric,Neud?rfl, J?rg-Martin,Goldfuss, Bernd. "Enantioselective Cu-catalyzed 1,4-additions of organozinc and Grignard reagents to enones: Exceptional performance of the hydrido-phosphite-ligand BIFOP-H". supporting information. p. 4787 - 4799. Retrieved 2019/03/26.