C₁₆H₁₇ClN₂O

Base Information

• Chemical Name: C₁₆H₁₇ClN₂O
• CAS No.: 1332336-56-7
• Molecular Formula: C₁₆H₁₇ClN₂O
• Molecular Weight: 288.777
• Mol file: 1332336-56-7.mol

Synonyms:

Chemical Property of C₁₆H₁₇ClN₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₇ClN₂O

There total 5 articles about C₁₆H₁₇ClN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloro-4-methoxypyridine-3-carbaldehyde (1256823-05-8) → C16H17ClN2O (1332336-56-7)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene

2: tetrahydrofuran

3: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 90 °C

4: dimethylsulfide borane complex; cyclohexene / tetrahydrofuran

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; dimethylsulfide borane complex; diphenylphosphoranyl azide; sodium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; cyclohexene; In tetrahydrofuran; water; toluene; 1: Suzuki coupling;

DOI:10.1016/j.bmcl.2011.06.014

Reference yield:

C13H10ClNO2 (1332336-59-0) → C16H17ClN2O (1332336-56-7)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran

2: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 90 °C

3: dimethylsulfide borane complex; cyclohexene / tetrahydrofuran

With dimethylsulfide borane complex; diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; cyclohexene; In tetrahydrofuran; toluene;

DOI:10.1016/j.bmcl.2011.06.014

Reference yield:

C16H16ClNO2 (1332336-61-4) → C16H17ClN2O (1332336-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 90 °C

2: dimethylsulfide borane complex; cyclohexene / tetrahydrofuran

With dimethylsulfide borane complex; diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; cyclohexene; In tetrahydrofuran; toluene;

DOI:10.1016/j.bmcl.2011.06.014

upstream raw materials:

6-chloro-4-methoxypyridine-3-carbaldehyde

C₁₃H₁₀ClNO₂

C₁₆H₁₆ClNO₂

C₁₆H₁₅ClN₄O

Downstream raw materials:

C₂₀H₁₈ClN₃O₂S

C₂₁H₂₃ClN₂O₂