2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER

Base Information

Chemical Name:2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER
CAS No.:139891-43-3
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:
Mol file:139891-43-3.mol

Synonyms:H-D-Hph-OMe;β-phenylalanine methyl ester;

Suppliers and Price of 2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER

Chemical Property:

PSA：52.32000
LogP:1.81980

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER

There total 6 articles about 2-AMINO-4-PHENYL-BUTYRIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 82795-51-5
D-homophenylalanine

: 77-76-9
2,2-dimethoxy-propane

: 139891-43-3
2-(R)-amino-4-phenylbutyric acid methyl ester

Guidance literature:: With hydrogenchloride; for 48h;
DOI:10.1039/b417954d

Reference yield:

: 262846-59-3
methyl 2-(2-methoxy-6-methylphenyl)amino-4-phenylbutanoate

: 139891-43-3
2-(R)-amino-4-phenylbutyric acid methyl ester

Guidance literature:: With ammonium cerium(IV) nitrate; trifluoroacetic acid; In methanol; water; at 0 ℃;
DOI:10.1021/ja9935207

Reference yield:

: methyl (5-phenylpent-1-en-3-yl) carbonate

: 139891-43-3
2-(R)-amino-4-phenylbutyric acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) lithium hexamethyldisilylazide, 2.) Ph(PPh₃)3Cl, P(OMe)3 / 1.) THF, 30 deg C, 30 min, 2.) THF, 30 deg C, 3 h

2: O₃, aq. NaOH

3: PhSH, K₂CO₃ / dimethylformamide

4: H₂ / Pd(OH)2

With sodium hydroxide; Ph(PPh₃)3Cl; hydrogen; potassium carbonate; ozone; thiophenol; lithium hexamethyldisilazane; phosphorous acid trimethyl ester; palladium dihydroxide; In N,N-dimethyl-formamide;
DOI:10.1021/ja991089f