trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester

Base Information

• Chemical Name: trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester
• CAS No.: 322765-97-9
• Molecular Formula: C₄₂H₄₀F₃NO₁₀
• Molecular Weight: 775.776
• Mol file: 322765-97-9.mol

Synonyms:

Chemical Property of trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester

There total 1 articles about trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoroacetic anhydride (407-25-0) + {3,4-bis-(3,4-dimethoxy-phenyl)-1-[2-(3,4-dimethoxy-phenyl)-ethyl]-1H-pyrrol-2-yl}-(3,4-dimethoxy-phenyl)-acetic acid (322765-96-8) → trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester (322765-97-9)

Guidance literature:

With potassium trifluoroacetate; In dichloromethane; at 45 ℃; for 4h;

DOI:10.1016/S0040-4039(00)01614-2

Reference yield:

trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester (322765-97-9) → permethyl ningalin C (322765-98-0)

Guidance literature:

With sodium hydroxide; In methanol; at 25 ℃; for 18h;

DOI:10.1016/S0040-4039(00)01614-2

Reference yield:

trifluoro-acetic acid 1,4-bis-(3,4-dimethoxy-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethyl]-7,8-dimethoxy-3H-benzo[e]indol-5-yl ester (322765-97-9) → Ningalin C

Guidance literature:

Multi-step reaction with 2 steps

1: 10 percent aq. NaOH / methanol / 18 h / 25 °C

2: 90 percent / BBr₃; cyclohexene / CH₂Cl₂ / 18 h / -78 - 25 °C

With sodium hydroxide; boron tribromide; cyclohexene; In methanol; dichloromethane;

DOI:10.1016/S0040-4039(00)01614-2

upstream raw materials:

trifluoroacetic anhydride

{3,4-bis-(3,4-dimethoxy-phenyl)-1-[2-(3,4-dimethoxy-phenyl)-ethyl]-1H-pyrrol-2-yl}-(3,4-dimethoxy-phenyl)-acetic acid

Downstream raw materials:

permethyl ningalin C