Technology Process of trans-3-hydroxy-2-methylcyclohexanone
There total 8 articles about trans-3-hydroxy-2-methylcyclohexanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium fluoride; dihydrogen peroxide; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; water;
for 72h;
stereoselective reaction;
Inert atmosphere;
DOI:10.1039/c5ob02402a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium / tetrahydrofuran / 0 °C / Inert atmosphere
1.2: 2 h / 0 °C / Inert atmosphere
2.1: boron trifluoride diacetate / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
3.1: dihydrogen peroxide; potassium fluoride; sodium hydrogencarbonate / tetrahydrofuran; water; methanol / 72 h / Inert atmosphere
With
potassium fluoride; dihydrogen peroxide; boron trifluoride diacetate; lithium; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; dichloromethane; water;
3.1: |Tamao-Kumada Oxidation;
DOI:10.1039/c5ob02402a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: boron trifluoride diacetate / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
2: dihydrogen peroxide; potassium fluoride; sodium hydrogencarbonate / tetrahydrofuran; water; methanol / 72 h / Inert atmosphere
With
potassium fluoride; dihydrogen peroxide; boron trifluoride diacetate; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; dichloromethane; water;
2: |Tamao-Kumada Oxidation;
DOI:10.1039/c5ob02402a
