Z-(RS)-Phe(2Br)-OCH₂CH₂Cl

Base Information

• Chemical Name: Z-(RS)-Phe(2Br)-OCH₂CH₂Cl
• CAS No.: 423763-14-8
• Molecular Formula: C₁₉H₁₉BrClNO₄
• Molecular Weight: 440.721
• Mol file: 423763-14-8.mol

Synonyms:

Chemical Property of Z-(RS)-Phe(2Br)-OCH₂CH₂Cl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-(RS)-Phe(2Br)-OCH₂CH₂Cl

There total 5 articles about Z-(RS)-Phe(2Br)-OCH₂CH₂Cl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-(RS)-Phe(2Br)-OCH2CF3 (203640-55-5) → Z-(RS)-Phe(2Br)-OCH2CH2Cl (423763-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.4 percent Chromat. / Et3N; α-chymotrypsin immobilised on Celite / acetonitrile; various solvent(s) / 1 h / 30 °C / pH 7.8

2: DMAP; EDC*HCl / CH₂Cl₂

With dmap; α-chymotrypsin immobilised on Celite; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1039/b108735p

Reference yield:

z-(RS)-Phe(2Br)-O-carbamoylmethyl (203640-56-6) → Z-(RS)-Phe(2Br)-OCH2CH2Cl (423763-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 8.8 percent Chromat. / Et3N; α-chymotrypsin immobilised on Celite / acetonitrile; various solvent(s) / 1 h / 30 °C / pH 7.8

2: DMAP; EDC*HCl / CH₂Cl₂

With dmap; α-chymotrypsin immobilised on Celite; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1039/b108735p

Reference yield:

Z-(RS)-Phe(2Br)-ON=C(CH3)2 (423763-16-0) → Z-(RS)-Phe(2Br)-OCH2CH2Cl (423763-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.1 percent Chromat. / Et3N; α-chymotrypsin immobilised on Celite / acetonitrile; various solvent(s) / 1 h / 30 °C / pH 7.8

2: DMAP; EDC*HCl / CH₂Cl₂

With dmap; α-chymotrypsin immobilised on Celite; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1039/b108735p

upstream raw materials:

Z-DL-Phe(2Br)

2-chloro-ethanol

z-(RS)-Phe(2Br)-O-carbamoylmethyl

Z-(RS)-Phe(2Br)-OCH₂CF₃