Technology Process of C27H35NO4Si
There total 6 articles about C27H35NO4Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrachloromethane; (4S,4'S)-2,2'-(4-bromopyridine-2,6-diyl)bis(4-tert-butyl-4,5-dihydrooxazole); magnesium iodide;
at 20 ℃;
for 72h;
Inert atmosphere;
Molecular sieve;
Glovebox;
DOI:10.1021/ol4010646
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 1.25 h / 0 - 20 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: magnesium iodide; (4S,4'S)-2,2'-(4-bromopyridine-2,6-diyl)bis(4-tert-butyl-4,5-dihydrooxazole); tetrachloromethane / 72 h / 20 °C / Inert atmosphere; Molecular sieve; Glovebox
With
tetrachloromethane; (4S,4'S)-2,2'-(4-bromopyridine-2,6-diyl)bis(4-tert-butyl-4,5-dihydrooxazole); sodium hydride; magnesium iodide;
In
tetrahydrofuran;
2.1: |Friedel-Crafts Alkylation;
DOI:10.1021/ol4010646
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 1.25 h / 0 - 20 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: magnesium iodide; (4S,4'S)-2,2'-(4-bromopyridine-2,6-diyl)bis(4-tert-butyl-4,5-dihydrooxazole); tetrachloromethane / 72 h / 20 °C / Inert atmosphere; Molecular sieve; Glovebox
With
tetrachloromethane; (4S,4'S)-2,2'-(4-bromopyridine-2,6-diyl)bis(4-tert-butyl-4,5-dihydrooxazole); sodium hydride; magnesium iodide;
In
tetrahydrofuran;
2.1: |Friedel-Crafts Alkylation;
DOI:10.1021/ol4010646
