C₃₀H₃₂N₄O₂

Base Information

• Chemical Name: C₃₀H₃₂N₄O₂
• CAS No.: 1569272-96-3
• Molecular Formula: C₃₀H₃₂N₄O₂
• Molecular Weight: 480.61
• Mol file: 1569272-96-3.mol

Synonyms:

Chemical Property of C₃₀H₃₂N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₂N₄O₂

There total 6 articles about C₃₀H₃₂N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H18BrNO2 (1569273-00-2) → C30H32N4O2 (1569272-96-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium phosphate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane; water / 0.5 h / 140 °C / Inert atmosphere; Microwave irradiation

2.1: ozone / dichloromethane / 0.08 h / -78 °C

2.2: resin-bound triphenylphosphine / Inert atmosphere

3.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 15 h

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium tris(acetoxy)borohydride; ozone; tricyclohexylphosphine; In 1,4-dioxane; dichloromethane; water; 1,2-dichloro-ethane; 1.1: |Suzuki Coupling;

DOI:10.1021/ml500055h

Reference yield:

1-hydroxy-naphthalene-2-carboxylic acid methyl ester (948-03-8) → C30H32N4O2 (1569272-96-3)

Guidance literature:

Multi-step reaction with 8 steps

1.1: pyridine / 1 h / -5 °C

2.1: lithium chloride; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 3 h / 110 °C / Inert atmosphere

3.1: bromine; acetic acid / 19 h / 20 - 90 °C / Inert atmosphere

4.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 1 h / 90 °C / Inert atmosphere

5.1: tetrahydrofuran / 15 h

6.1: potassium phosphate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane; water / 0.5 h / 140 °C / Inert atmosphere; Microwave irradiation

7.1: ozone / dichloromethane / 0.08 h / -78 °C

7.2: resin-bound triphenylphosphine / Inert atmosphere

8.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 15 h

With pyridine; bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; bromine; sodium tris(acetoxy)borohydride; ozone; acetic acid; lithium chloride; tricyclohexylphosphine; dibenzoyl peroxide; In tetrahydrofuran; 1,4-dioxane; tetrachloromethane; dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; 2.1: |Stille Cross Coupling / 6.1: |Suzuki Coupling;

DOI:10.1021/ml500055h

Reference yield:

1-(((trifluoromethyl)sulfonyl)oxy)-2-naphthoic acid methyl ester → C30H32N4O2 (1569272-96-3)

Guidance literature:

Multi-step reaction with 7 steps

1.1: lithium chloride; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 3 h / 110 °C / Inert atmosphere

2.1: bromine; acetic acid / 19 h / 20 - 90 °C / Inert atmosphere

3.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 1 h / 90 °C / Inert atmosphere

4.1: tetrahydrofuran / 15 h

5.1: potassium phosphate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane; water / 0.5 h / 140 °C / Inert atmosphere; Microwave irradiation

6.1: ozone / dichloromethane / 0.08 h / -78 °C

6.2: resin-bound triphenylphosphine / Inert atmosphere

7.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 15 h

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; bromine; sodium tris(acetoxy)borohydride; ozone; acetic acid; lithium chloride; tricyclohexylphosphine; dibenzoyl peroxide; In tetrahydrofuran; 1,4-dioxane; tetrachloromethane; dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; 1.1: |Stille Cross Coupling / 5.1: |Suzuki Coupling;

DOI:10.1021/ml500055h

upstream raw materials:

C₁₈H₁₈BrNO₂

1-hydroxy-naphthalene-2-carboxylic acid methyl ester

C₂₀H₂₁NO₂

C₁₉H₁₉NO₃