8-Hydroxypinoresinol

Base Information

• Chemical Name: 8-Hydroxypinoresinol
• CAS No.: 81426-17-7
• Molecular Formula: C₂₀H₂₂O₇
• Molecular Weight: 374.39
• DSSTox Substance ID: DTXSID001315412
• Nikkaji Number: J564.477A
• Wikidata: Q104959632
• Metabolomics Workbench ID: 137426
• ChEMBL ID: CHEMBL471274
• Mol file: 81426-17-7.mol

Synonyms:8-hydroxypinoresinol

Chemical Property of 8-Hydroxypinoresinol

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 374.13655304
• Heavy Atom Count: 27
• Complexity: 517

Purity/Quality:

Analysis control,HPLC≥95% ^*data from raw suppliers

8-Hydroxypinoresinol ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C2C3COC(C3(CO2)O)C4=CC(=C(C=C4)O)OC)O
• Isomeric SMILES: COC1=C(C=CC(=C1)[C@@H]2[C@H]3CO[C@@H]([C@]3(CO2)O)C4=CC(=C(C=C4)O)OC)O

Technology Process of 8-Hydroxypinoresinol

There total 5 articles about 8-Hydroxypinoresinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-1-hydroxypinoresinol 4',4-di-O-β-D-glucopyranoside (112747-99-6) → 8'-hydroxypinoresinol (81446-27-7,96894-15-4,81426-17-7)

Guidance literature:

With β-glucosidase; In various solvent(s); at 37 ℃; for 72h;

DOI:10.1248/cpb.33.3651

Reference yield:

(+)-1-acetoxypinoresinol (96894-13-2,96894-14-3,81426-14-4) → 8'-hydroxypinoresinol (81446-27-7,96894-15-4,81426-17-7)

Guidance literature:

With ammonia; In methanol;

DOI:10.1248/cpb.32.2730

Reference yield:

(+)-1-hydroxypinoresinol-4'-O-β-D-glucopyranoside (72896-51-6) → D-Glucose (2280-44-6) + 8'-hydroxypinoresinol (81446-27-7,96894-15-4,81426-17-7)

Guidance literature:

With β-glucosidase; In various solvent(s); at 37 ℃; for 24h; Product distribution; pH=5.0;

DOI:10.1248/cpb.34.523

upstream raw materials:

(+)-1-hydroxypinoresinol 4',4-di-O-β-D-glucopyranoside

(+)-1-acetoxypinoresinol

(+)-1-hydroxypinoresinol-4'-O-β-D-glucopyranoside

(+)-1-hydroxypinoresinol-4''-O-β-D-glucopyranoside

Downstream raw materials:

4-ethoxy-3-methoxybenzoic acid

(+)-1-hydroxy-2-epipinoresinol

(+)-1-hydroxypinoresinol diacetate

neogmelinol