thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone

Base Information

• Chemical Name: thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone
• CAS No.: 1435-02-5
• Molecular Formula: C₁₃H₁₃N₃S₂
• Molecular Weight: 275.398
• Mol file: 1435-02-5.mol

Synonyms:

Chemical Property of thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone

There total 1 articles about thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

thiophene-2-carbaldehyde (98-03-3) + 4-(4-methylphenyl)-3-thiosemicarbazide (13278-67-6) → thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone (1435-02-5)

Guidance literature:

In ethanol; water; at 25 ℃; for 3h;

DOI:10.1016/j.ejmech.2006.01.014

Reference yield: 65.0%

thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone (1435-02-5) + vanadyl(IV) sulphate pentahydrate → VO(C13H12N3S2)2 (198222-42-3)

Guidance literature:

With potassium hydroxide; In methanol; ethanol; addn. of soln. of ligand to soln. of VO-salt (both in MeOH), addn. of satd. alcoholic soln. of reagent, refluxing (16 h, pptn.); filtration, washing (H2O, EtOH), drying (vac.); elem. anal.;

DOI:10.1080/00945719708000157

Reference yield:

thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone (1435-02-5) + tris(triphenylphosphine)ruthenium(II) chloride (15529-49-4,41756-81-4) → [Ru(thiophen-2-carbaldehyde 4'-(4''-methyl)phenyl-thiosemicarbazone)2(PPh3)2]

Guidance literature:

With triethyl amine; In methanol; to methanolic soln. of thiosemicarbazone ligand, Et3N was added, addn. of Ru(PPh3)3Cl2 to deprotonated ligand changes the colour immediately, react. mixt. refluxed for 1-2 h, solid appeared during the react.; filtered, washed (ether), dried (vac.); elem. anal., XRD;

DOI:10.1016/j.poly.2009.09.030

upstream raw materials:

thiophene-2-carbaldehyde

4-(4-methylphenyl)-3-thiosemicarbazide

Downstream raw materials:

VO(C₁₃H₁₂N₃S₂)2