1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride

Base Information

Chemical Name:1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride
CAS No.:1386928-34-2
Molecular Formula:C₁₇H₂₀N₂O*ClH
Molecular Weight:304.82
Hs Code.:
Mol file:1386928-34-2.mol

Synonyms:

Suppliers and Price of 1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4''-Methoxy[1,1''-biphenyl]-2-yl)-piperazineHydrochloride
100mg
$ 1175.00

TRC
1-(4''-Methoxy[1,1''-biphenyl]-2-yl)-piperazineHydrochloride
10mg
$ 145.00

Medical Isotopes, Inc.
1-(4??-Methoxy[1,1??-biphenyl]-2-yl)-piperazineHCl
10 mg
$ 640.00

ApexBio Technology
LP20hydrochloride
50mg
$ 1090.00

ApexBio Technology
LP20hydrochloride
10mg
$ 257.00

American Custom Chemicals Corporation
1-(4'-METHOXY[1,1'-BIPHENYL]-2-YL)-PIPERAZINE HYDROCHLORIDE 95.00%
5MG
$ 499.94

Total 9 raw suppliers

Chemical Property of 1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride

Chemical Property:

Purity/Quality:

≥98% by HPLC ^*data from raw suppliers

1-(4''-Methoxy[1,1''-biphenyl]-2-yl)-piperazineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride showed 5-HT7 agonist properties in a guinea pig ileum assay but blocked 5-HT-mediated cAMP accumulation in 5-HT7-expressing HeLa cells. 1-(4''-Methoxy[1,1''-biphenyl]-2-yl)-piperazine Hydrochloride showed 5-HT7 agonist properties in a guinea pig ileum assay but blocked 5-HT-mediated cAMP accumulation in 5-HT7-expressing HeLa cells.

Technology Process of 1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride

There total 2 articles about 1-(4'-Methoxy[1,1'-biphenyl]-2-yl)-piperazine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 38089-03-1
2-(4-methoxyphenyl)aniline

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 1386928-34-2
1-[2-(4-methoxyphenyl)phenyl]piperazine hydrochloride

Guidance literature:: With potassium carbonate; potassium iodide; for 48h; Reflux;
DOI:10.1021/jm3003679

Reference yield:

: 615-43-0
2-iodophenylamine

: 5720-07-0
4-methoxyphenylboronic acid

: 1386928-34-2
1-[2-(4-methoxyphenyl)phenyl]piperazine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide / tetrahydrofuran / 12 h / Reflux

2: potassium carbonate; potassium iodide / 48 h / Reflux

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; potassium iodide; sodium hydroxide; In tetrahydrofuran; 1: Suzuki coupling;
DOI:10.1021/jm3003679