(2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride

Base Information

Chemical Name:(2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride
CAS No.:702629-88-7
Molecular Formula:C₁₂H₁₄ClNO
Molecular Weight:223.702
Hs Code.:
DSSTox Substance ID:DTXSID401219636
Mol file:702629-88-7.mol

Synonyms:702629-88-7;(2s)-1-(phenylmethyl)-2-pyrrolidinecarbonyl chloride;SCHEMBL3055319;DTXSID401219636

Suppliers and Price of (2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
(S)-1-benzyl-pyrrolidine-2-carbonylchloride 95
5g
$ 1833.00

Total 1 raw suppliers

Chemical Property of (2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:223.0763918
Heavy Atom Count:15
Complexity:226

Purity/Quality:: (S)-1-benzyl-pyrrolidine-2-carbonylchloride 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)CC2=CC=CC=C2)C(=O)Cl
Isomeric SMILES:C1C[C@H](N(C1)CC2=CC=CC=C2)C(=O)Cl

Technology Process of (2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride

There total 7 articles about (2s)-1-(Phenylmethyl)-2-pyrrolidinecarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 31795-93-4
N-benzyl-L-proline

: 105099-19-2,702629-88-7
N-benzyl-(S)-proline chloroanhydride

Guidance literature:: With thionyl chloride; for 3h; Ambient temperature;
DOI:10.1021/ja00345a057

Reference yield:

: 56080-99-0
(D)-1-benzylpyrrolidine-2-carboxylic acid

: 702629-88-7
C₁₂H₁₄ClNO

Guidance literature:: With thionyl chloride; In dichloromethane; at -20 - 30 ℃;

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 105099-19-2,702629-88-7
N-benzyl-(S)-proline chloroanhydride

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / KOH / propan-2-ol / 6 h / 40 °C

2: SOCl₂ / CH₂Cl₂ / -10 °C

With potassium hydroxide; thionyl chloride; In dichloromethane; isopropyl alcohol;
DOI:10.1016/S0957-4166(98)00449-2