(2S)-1-benzylpyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(2S)-1-benzylpyrrolidine-2-carboxylic acid
CAS No.:31795-93-4
Molecular Formula:C12H15NO2
Molecular Weight:205.257
Hs Code.:2933990090
European Community (EC) Number:640-145-2
DSSTox Substance ID:DTXSID20352538
Nikkaji Number:J488.660G
Mol file:31795-93-4.mol

Synonyms:N-benzyl-L-proline

Suppliers and Price of (2S)-1-benzylpyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
1-Benzyl-L-proline 97%
25g
$ 330.00

Activate Scientific
(S)-1-Benzylpyrrolidine-2-carboxylic acid 98% ee
25 g
$ 383.00

Activate Scientific
(S)-1-Benzylpyrrolidine-2-carboxylic acid 98% ee
1 g
$ 43.00

Activate Scientific
(S)-1-Benzylpyrrolidine-2-carboxylic acid 98% ee
5 g
$ 115.00

AK Scientific
(2S)-1-Benzylpyrrolidine-2-carboxylicacid
5g
$ 151.00

Alichem
(S)-1-Benzylpyrrolidine-2-carboxylicacid
25g
$ 260.00

Ambeed
(S)-1-Benzylpyrrolidine-2-carboxylicacid 98%
25g
$ 245.00

Ambeed
(S)-1-Benzylpyrrolidine-2-carboxylicacid 98%
100g
$ 725.00

Ambeed
(S)-1-Benzylpyrrolidine-2-carboxylicacid 98%
10g
$ 123.00

Ambeed
(S)-1-Benzylpyrrolidine-2-carboxylicacid 98%
5g
$ 68.00

Total 57 raw suppliers

Chemical Property of (2S)-1-benzylpyrrolidine-2-carboxylic acid

Chemical Property:

Appearance/Colour:white solid
Vapor Pressure:2.76E-05mmHg at 25°C
Melting Point:168-171oC
Refractive Index:1.587
Boiling Point:343.1 °C at 760 mmHg
PKA:2.35±0.20(Predicted)
Flash Point:161.3 °C
PSA：40.54000
Density:1.205 g/cm³
LogP:1.67350
Storage Temp.:Store at 0-5°C
Solubility.:Acetone (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

1-Benzyl-L-proline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(N(C1)CC2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1C[C@H](N(C1)CC2=CC=CC=C2)C(=O)O
Uses A reagent for the synthesis of optically pure a-amino-acids A reagent for the synthesis of optically pure α-amino-acids.

Technology Process of (2S)-1-benzylpyrrolidine-2-carboxylic acid

There total 13 articles about (2S)-1-benzylpyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.2%

: 100-52-7
benzaldehyde

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 31795-93-4
N-benzyl-L-proline

Guidance literature:: With hydrogen; Wilkinson's catalyst; In methanol; at 20 ℃; for 72h; under 37503 Torr;
DOI:10.1055/s-2004-830855

Reference yield: 92.0%

: 100-39-0
benzyl bromide

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 31795-93-4
N-benzyl-L-proline

Guidance literature:: benzyl bromide; L-proline; With potassium hydroxide; In isopropyl alcohol; at 40 ℃;

With hydrogenchloride; In chloroform; water; isopropyl alcohol; at 20 ℃; for 12h; pH=4 - 5;
DOI:10.3390/molecules22101766