2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide

Base Information

Chemical Name:2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide
CAS No.:58939-41-6
Molecular Formula:C₂₁H₂₆NO₄*I
Molecular Weight:483.346
Hs Code.:
DSSTox Substance ID:DTXSID70572789
NSC Number:379964

Synonyms:58939-41-6;DTXSID70572789;NSC379964;NSC-379964;2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide

Suppliers and Price of 2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:483.09066
Heavy Atom Count:27
Complexity:502

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[N+]12CCC3=CC(=C(C=C3C1CC4=CC(=C(C=C24)OC)OC)OC)OC.[I-]

Technology Process of 2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide

There total 18 articles about 2,3,9,10-Tetramethoxy-7-methyl-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinolin-7-ium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 21162-73-2
5,6,12,12a-Tetrahydro-2,3,9,10-tetramethoxy-indolo<2,1-a>isoquinoline

: 74-88-4
methyl iodide

: 58939-41-6
O-methylcryptaustoline iodide

Guidance literature:: In methanol; at 20 ℃; for 48h;
DOI:10.3987/com-99-8838

Reference yield: 25.0%

: 1361538-07-9
N-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dimethoxybenzylidene)-2-phenylaziridin-1-amine

: 74-88-4
methyl iodide

: 58939-41-6
O-methylcryptaustoline iodide

Guidance literature:: N-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dimethoxybenzylidene)-2-phenylaziridin-1-amine; With dirhodium(II) tetrakis(methyl 2-oxopyrrolidine-5(S)-carboxylate); In toluene; at 100 ℃; for 6h; Inert atmosphere;

methyl iodide; In methanol; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1002/chem.201103155

Reference yield:

: 83573-15-3
2-<(3',4'-dimethoxy-6'-nitrophenylacetyl)-4,5-dimethoxy>phenylacetic acid

: 58939-41-6
O-methylcryptaustoline iodide

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / concd. sulfuric acid / 2 h / Heating

2: 71 percent / hydrogen / 10 percent Pd/C / methanol; propan-2-ol / 1 h / 912 Torr

3: 78 percent / p-toluenesulfonic acid / CH₂Cl₂ / 3.5 h / 20 °C

4: zinc powder; concd. hydrochloric acid / acetic acid; H₂O / 1.5 h / Heating

5: 55 percent / methanol / 48 h / 20 °C

With hydrogenchloride; sulfuric acid; hydrogen; toluene-4-sulfonic acid; zinc; palladium on activated charcoal; In methanol; dichloromethane; water; acetic acid; isopropyl alcohol; 1: Esterification / 2: Reduction / 3: Cyclization / 4: Reduction / 5: Methylation;
DOI:10.3987/com-99-8838