(R)-2-Nitro-α-MethylbenzylaMine Hydrochloride

Base Information

• Chemical Name: (R)-2-Nitro-α-MethylbenzylaMine Hydrochloride
• CAS No.: 1431699-56-7
• Molecular Formula: C₈H₁₀N₂O₂*(x)ClH
• Molecular Weight: 202.64
• Mol file: 1431699-56-7.mol

Synonyms:

Chemical Property of (R)-2-Nitro-α-MethylbenzylaMine Hydrochloride

Chemical Property:

• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99%+, ^*data from raw suppliers

(R)-2-Nitro-α-methylbenzylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (R)-2-Nitro-α-MethylbenzylaMine Hydrochloride can be used in the construction of Nitroaromatic Peprides, such as N-substituted glycine oligomers, or peptiods, that have shown to have important applications for the study of biomolecular interaction, and also for their use as therapeutic agents. 2-Nitro-α-methyl-benzylamine Hydrochloride, can be used in the construction of Nitroaromatic Peprides, such as N-substituted glycine oligomers, or peptiods, that have shown to have important applications for the study of biomolecular interaction, and also for their use as therapeutic agents.

Technology Process of (R)-2-Nitro-α-MethylbenzylaMine Hydrochloride

There total 4 articles about (R)-2-Nitro-α-MethylbenzylaMine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-((S)-1-(2-nitrophenyl)ethyl)acetamide (1117218-57-1) → (S)-1-(2)-(nitrophenyl)ethylamine hydrochloride (1113041-80-7,1431699-56-7,148657-37-8)

Guidance literature:

With hydrogenchloride; In water; for 14h; Reflux;

DOI:10.1021/jo8023363

Reference yield: 50.0%

o-nitroacetophenone O-methyl oxime (288591-69-5) → 2-Nitro-α-phenethylamine hydrochloride (1431699-56-7,148657-37-8)

Guidance literature:

With borane; In tetrahydrofuran; for 6h; Heating;

DOI:10.1021/jo9917846

Reference yield:

1-(2-nitrophenyl)ethylamine (100311-54-4) → 2-Nitro-α-phenethylamine hydrochloride (1431699-56-7,148657-37-8)

Guidance literature:

With hydrogenchloride; In dichloromethane; water; for 1h;

upstream raw materials:

o-nitroacetophenone O-methyl oxime

2-acetylnitrobenzene

1-(2-nitrophenyl)ethylamine

N-((S)-1-(2-nitrophenyl)ethyl)acetamide

Refernces

• 1、 Fowler, Sarah A.,Luechapanichkul, Rinrada,Blackwell, Helen E.. "Synthesis and Characterization of Nitroaromatic Peptoids: Fine Tuning Peptoid Secondary Structure through Monomer Position and Functionality". experimental part. p. 1440 - 1449. Retrieved 2009/07/30.