1-AMINO-3-METHOXY-PROPAN-2-OL HYDROCHLORIDE

Base Information

• Chemical Name: 1-AMINO-3-METHOXY-PROPAN-2-OL HYDROCHLORIDE
• CAS No.: 60812-33-1
• Molecular Formula: C₄H₁₁NO₂*ClH
• Molecular Weight: 141.598
• Mol file: 60812-33-1.mol

Synonyms:

Chemical Property of 1-AMINO-3-METHOXY-PROPAN-2-OL HYDROCHLORIDE

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

1-Amino-3-methoxy-propan-2-olhydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 1-AMINO-3-METHOXY-PROPAN-2-OL HYDROCHLORIDE

There total 2 articles about 1-AMINO-3-METHOXY-PROPAN-2-OL HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-3-methoxypropan-2-ol (4151-97-7) → DL-3-amino-1-methoxypropan-2-ol hydrochloride (60812-33-1)

Guidance literature:

With ammonium hydroxide; In water; at 0 ℃; for 2h;

DOI:10.1021/ja00310a044

Reference yield:

C17H19NO2 → DL-3-amino-1-methoxypropan-2-ol hydrochloride (60812-33-1)

Guidance literature:

With hydrogenchloride; In water; ethyl acetate; at 60 ℃; for 0.5h; pH=< 4;

DOI:10.1021/acs.oprd.8b00133

Reference yield:

DL-3-amino-1-methoxypropan-2-ol hydrochloride (60812-33-1) + benzoyl chloride (98-88-4) → N-(2-hydroxy-3-methoxypropyl)benzamide

Guidance literature:

DL-3-amino-1-methoxypropan-2-ol hydrochloride; With NaOH or DIPEA; In 2-methyltetrahydrofuran; water; at 20 - 25 ℃;

benzoyl chloride; In 2-methyltetrahydrofuran; water; at 20 - 25 ℃;

DOI:10.1021/acs.oprd.8b00133

upstream raw materials:

1-chloro-3-methoxypropan-2-ol

Refernces

• 1、 Crans, Debbie C.,Whitesides, George M.. "Glycerol kinase: substrate specificity.". . p. 7008 - 7018. Retrieved 2007/10/02.