1,3-dimethyl-8-β-D-ribofuranosylxanthine

Base Information

• Chemical Name: 1,3-dimethyl-8-β-D-ribofuranosylxanthine
• CAS No.: 115334-79-7
• Molecular Formula: 2C₁₂H₁₆N₄O₆*H₂O
• Molecular Weight: 642.58
• Mol file: 115334-79-7.mol

Synonyms:

Chemical Property of 1,3-dimethyl-8-β-D-ribofuranosylxanthine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dimethyl-8-β-D-ribofuranosylxanthine

There total 5 articles about 1,3-dimethyl-8-β-D-ribofuranosylxanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

8-(5-O-benzoyl-β-D-ribofuranosyl)-1,3-dimethylxanthine (108967-26-6) → 1,3-dimethyl-8-β-D-ribofuranosylxanthine (115334-79-7)

Guidance literature:

With ammonia; for 19h; Ambient temperature;

DOI:10.1016/S0008-6215(00)90269-6

Reference yield:

5-O-benzoyl-β-D-ribofuranosyl cyanide (30002-87-0) → 1,3-dimethyl-8-β-D-ribofuranosylxanthine (115334-79-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 79 percent / HCl gas / diethyl ether / 0 °C

2: 9 percent / pyridine / 2 h / Heating

3: 91 percent / methanolic ammonia / 19 h / Ambient temperature

With pyridine; hydrogenchloride; ammonia; In diethyl ether;

DOI:10.1016/S0008-6215(00)90269-6

Reference yield:

5,6-Diamino-1,3-dimethyluracil hydrate → 1,3-dimethyl-8-β-D-ribofuranosylxanthine (115334-79-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 30 h / Heating

2: 91 percent / methanolic ammonia / 19 h / Ambient temperature

With ammonia; In ethanol;

DOI:10.1016/S0008-6215(00)90269-6

upstream raw materials:

8-(5-O-benzoyl-β-D-ribofuranosyl)-1,3-dimethylxanthine

5-O-benzoyl-β-D-ribofuranosyl cyanide

ethyl 2,5-anhydro-6-O-benzoyl-D-allonodithioate

ethyl 2,5-anhydro-6-O-benzoyl-D-allonothioimidate hydrochloride