Monoacetylfolic Acid Azlactone

Base Information

• Chemical Name: Monoacetylfolic Acid Azlactone
• CAS No.: 78168-19-1
• Molecular Formula: C₂₁H₁₉N₇O₆
• Molecular Weight: 465.425
• Mol file: 78168-19-1.mol

Synonyms:

Chemical Property of Monoacetylfolic Acid Azlactone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Monoacetylfolic Acid Azlactone

There total 1 articles about Monoacetylfolic Acid Azlactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

folate (65165-92-6) + acetic anhydride (108-24-7) → 4-[Acetyl-(2-amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl)-amino]-benzoic acid (78168-22-6) + Monoacetylfolic Acid Azlactone (78168-19-1) + Diacetylfolic Acid Azlactone (78168-20-4) + 10,N2-diacetyl-pteroic acid (70844-36-9)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) Acetic acid, 1 h, reflux; 2.) H₂O (pH 8.8), 18 h, room temp.;

DOI:10.1021/jo00331a016

upstream raw materials:

folate

acetic anhydride