3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid

Base Information

Chemical Name:3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid
CAS No.:1332529-63-1
Molecular Formula:C₁₅H₁₈FN₃O*ClH
Molecular Weight:311.787
Hs Code.:
Mol file:1332529-63-1.mol

Synonyms:

Suppliers and Price of 3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Matrix Scientific
3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
500mg
$ 237.00

Total 2 raw suppliers

Chemical Property of 3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid

There total 4 articles about 3-{[(3-Fluorobenzyl)oxy]methyl}-1-methyl-4,5,6,7-t etrahydro-1H-pyrazolo[4,3-c]pyridine hydrochlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₀H₂₆FN₃O₃

: 1332529-63-1
3‐{[(3‐fluorobenzyl)oxy]methyl}‐1‐methyl‐4,5,6,7‐tetrahydro‐1H‐pyrazolo[4,3‐c]pyridine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; Inert atmosphere; Sonication;
DOI:10.1002/ardp.202000275

Reference yield:

: 518990-23-3
5‐tert‐butyl 3‐ethyl 1,4,6,7‐tetrahydro‐5H‐pyrazolo[4,3‐c]pyridine‐3,5‐dicarboxylate

: 1332529-63-1
3‐{[(3‐fluorobenzyl)oxy]methyl}‐1‐methyl‐4,5,6,7‐tetrahydro‐1H‐pyrazolo[4,3‐c]pyridine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / toluene / 6 h / 20 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran / 0.25 h / 20 °C / Inert atmosphere

3.2: 7 h / Inert atmosphere; Reflux

4.1: hydrogenchloride / 1,4-dioxane / Inert atmosphere; Sonication

With hydrogenchloride; lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; 1,4-dioxane; toluene;
DOI:10.1002/ardp.202000275

Reference yield:

: 1142210-81-8
5-(tert-butyl) 3-ethyl 1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate

: 1332529-63-1
3‐{[(3‐fluorobenzyl)oxy]methyl}‐1‐methyl‐4,5,6,7‐tetrahydro‐1H‐pyrazolo[4,3‐c]pyridine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran / 0.25 h / 20 °C / Inert atmosphere

2.2: 7 h / Inert atmosphere; Reflux

3.1: hydrogenchloride / 1,4-dioxane / Inert atmosphere; Sonication

With hydrogenchloride; lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1002/ardp.202000275