MT-DADMe-ImmA

Base Information

Chemical Name:MT-DADMe-ImmA
CAS No.:653592-04-2
Molecular Formula:C₁₃H₁₉N₅OS
Molecular Weight:293.393
Hs Code.:
Mol file:653592-04-2.mol

Synonyms:

Suppliers and Price of MT-DADMe-ImmA

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
MT-DADMe-ImmA >98%
1 g
$ 2800.00

DC Chemicals
MT-DADMe-ImmA >98%
250 mg
$ 1400.00

DC Chemicals
MT-DADMe-ImmA >98%
100 mg
$ 700.00

Cayman Chemical
MT-DADMe-ImmA
25mg
$ 627.00

Cayman Chemical
MT-DADMe-ImmA
10mg
$ 268.00

Cayman Chemical
MT-DADMe-ImmA
5mg
$ 150.00

Cayman Chemical
MT-DADMe-ImmA
1mg
$ 32.00

Total 6 raw suppliers

Chemical Property of MT-DADMe-ImmA

Chemical Property:

Melting Point:108-110 °C
Boiling Point:566.1±50.0 °C(Predicted)
PKA:14.13±0.40(Predicted)
Density:1.412±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

MT-DADMe-ImmA >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description MT-DADMe-ImmA is an inhibitor of 5''-methylthioadenosine phosphorylase (MTAP; Ki = 1.7 nM). It increases levels of MTA , a product of polyamine metabolism, in FaDu human squamous cell carcinoma cells when used at a concentration of 1 μM. MT-DADMe-ImmA (5, 9, and 21 mg/kg per day for 28 days) reduces tumor growth in a FaDu mouse xenograft model.

Technology Process of MT-DADMe-ImmA

There total 24 articles about MT-DADMe-ImmA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 666831-19-2
(3R,4S)-1-[(7-benzyloxymethyl-9-deazaadenin-9-yl)methyl]-3-hydroxy-4-methylthiomethylpyrrolidine

: 653592-04-2
(3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-4-((methylthio)methyl)pyrrolidin-3-ol

Guidance literature:: With hydrogenchloride; In water; for 1.5h; Heating / reflux;

Reference yield: 48.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: (3S,4R)-3-hydroxy-4-(methylthiomethyl)pyrrolidine hydrochloride

: 2227-98-7
9-Deazaadenine

: 653592-04-2
(3S,4R)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxy-4-(methylthiomethyl)-pyrrolidine

Guidance literature:: formaldehyd; (3S,4R)-3-hydroxy-4-(methylthiomethyl)pyrrolidine hydrochloride; With sodium acetate; In 1,4-dioxane; water; for 0.0833333h;

9-Deazaadenine; In 1,4-dioxane; water; at 95 ℃; for 14h;
DOI:10.1016/j.bmc.2015.07.059