S-{3-[(3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)sulfanyl]propyl} O,O-dipropyl dithiophosphate

Base Information

• Chemical Name: S-{3-[(3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)sulfanyl]propyl} O,O-dipropyl dithiophosphate
• CAS No.: 667911-51-5
• Molecular Formula: C₁₈H₂₅N₄O₂PS₄
• Molecular Weight: 488.66
• Mol file: 667911-51-5.mol

Synonyms:

Chemical Property of S-{3-[(3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)sulfanyl]propyl} O,O-dipropyl dithiophosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-{3-[(3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)sulfanyl]propyl} O,O-dipropyl dithiophosphate

There total 2 articles about S-{3-[(3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)sulfanyl]propyl} O,O-dipropyl dithiophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.4%

dithiophosphoric acid S-(3-bromo-propyl) ester O,O'-dipropyl ester + 3-phenyl-6-mercapto-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole (13228-87-0) → dithiophosphoric acid S-[3-(3-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylsulfanyl)-propyl] ester O,O'-dipropyl ester (667911-51-5)

Guidance literature:

With sodium methylate; In methanol; Heating;

DOI:10.1080/10426500490422191

Reference yield:

3-phenyl-4-amino-5-mercapto-1,2,4-triazole (22706-11-2) → dithiophosphoric acid S-[3-(3-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylsulfanyl)-propyl] ester O,O'-dipropyl ester (667911-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 61.2 percent / KOH / methanol / 24 h / Heating

2: 57.4 percent / NaOMe / methanol / Heating

With potassium hydroxide; sodium methylate; In methanol;

DOI:10.1080/10426500490422191

upstream raw materials:

3-phenyl-6-mercapto-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole

3-phenyl-4-amino-5-mercapto-1,2,4-triazole