(CYCLOHEXYLMETHYL)ETHYLAMINE

Base Information

• Chemical Name: (CYCLOHEXYLMETHYL)ETHYLAMINE
• CAS No.: 14002-08-5
• Molecular Formula: C9H19N
• Molecular Weight: 141.257
• Hs Code.: 2921300090
• Mol file: 14002-08-5.mol

Synonyms:ethyl-cyclohexylmethyl-amine;cyclohexyl-N-ethylcarboxamide;N-ethyl-cyclohexanecarboxamide;N-Ethyl-cyclohexan-carboxamid;Hexahydrobenzoesaeure-aethylamid;N-(cyclohexylmethyl)-N-ethylamine;N-cyclohexylmethyl-ethylamine;N-ethyl-N-<(3-hydroxyphenyl)methyl>amine;Aethyl-cyclohexylmethyl-amin;N-Aethyl-cyclohexancarbamid;N-ethylcyclohexanemethylamine;N-ethylcyclohexylmethylamine;Cyclohexanecarboxamide,N-ethyl-(9CI);cyclohexylmethyl-ethyl-amine;

Chemical Property of (CYCLOHEXYLMETHYL)ETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.733mmHg at 25°C
• Boiling Point: 184.4oC at 760 mmHg
• Flash Point: 55.6oC
• PSA: 12.03000
• Density: 0.834g/cm3
• LogP: 2.56710

Purity/Quality:

98%min ^*data from raw suppliers

(CYCLOHEXYLMETHYL)ETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (CYCLOHEXYLMETHYL)ETHYLAMINE

There total 14 articles about (CYCLOHEXYLMETHYL)ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclohexylmethylamine (3218-02-8) + acetonitrile (75-05-8,26809-02-9) → N-(cyclohexylmethyl)-N-ethylamine (14002-08-5)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 36h; under 760.051 Torr;

DOI:10.1039/c1ob06303k

Reference yield: 88.0%

N-(phenylmethyl)acetamide (588-46-5) → N-(cyclohexylmethyl)-N-ethylamine (14002-08-5)

Guidance literature:

With hydrogen; hexarhodium hexadecacarbonyl; decacarbonyldirhenium⁽⁰⁾; In 1,2-dimethoxyethane; at 180 ℃; for 16h; under 76000 Torr;

DOI:10.1016/S0040-4039(96)01458-X

Reference yield: 73.0%

N-ethyl-N-<(3-hydroxyphenyl)methyl>amine (138324-59-1) → N-(cyclohexylmethyl)-N-ethylamine (14002-08-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Heating;

DOI:10.1248/cpb.39.3225

upstream raw materials:

cyclohexylmethylene diacetate

ethylamine

Cyclohexylmethyl bromide

N-ethyl-N-<(3-hydroxyphenyl)methyl>amine

Downstream raw materials:

N-Cyclohexylmethyl-N-ethyl-4-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-butyramide

Refernces

• 1、 Toyao, Takashi,Siddiki,Morita, Yoshitsugu,Kamachi, Takashi,Touchy, Abeda S.,Onodera, Wataru,Kon, Kenichi,Furukawa, Shinya,Ariga, Hiroko,Asakura, Kiyotaka,Yoshizawa, Kazunari,Shimizu, Ken-Ichi. "Rhenium-Loaded TiO2: A Highly Versatile and Chemoselective Catalyst for the Hydrogenation of Carboxylic Acid Derivatives and the N-Methylation of Amines Using H2 and CO2". supporting information. p. 14848 - 14859. Retrieved 2017/10/27.
• 2、 Ikawa, Takashi,Fujita, Yuki,Mizusaki, Tomoteru,Betsuin, Sae,Takamatsu, Haruki,Maegawa, Tomohiro,Monguchi, Yasunari,Sajiki, Hironao. "Selective N-alkylation of amines using nitriles under hydrogenation conditions: Facile synthesis of secondary and tertiary amines". supporting information; experimental part. p. 293 - 304. Retrieved 2012/02/01.