(1S)-1,4,4,6-tetramethyl-2,3-dihydro-1H,4H-3a,6a-propanopentalene

Base Information

• Chemical Name: (1S)-1,4,4,6-tetramethyl-2,3-dihydro-1H,4H-3a,6a-propanopentalene
• CAS No.: 76739-64-5
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 76739-64-5.mol

Synonyms:

Chemical Property of (1S)-1,4,4,6-tetramethyl-2,3-dihydro-1H,4H-3a,6a-propanopentalene

Chemical Property:

• Vapor Pressure: 0.0134mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S)-1,4,4,6-tetramethyl-2,3-dihydro-1H,4H-3a,6a-propanopentalene

There total 85 articles about (1S)-1,4,4,6-tetramethyl-2,3-dihydro-1H,4H-3a,6a-propanopentalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1R*,5S*,6S*)-2,2,6-trimethyl-4-methylidentricyclo[3.3.3.0]undecan (76685-69-3) → (±)-modhephene (76739-64-5)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; for 3h;

DOI:10.1039/a704260d

Reference yield: 100.0%

(3aS,4S,6aR)-1,1,3,4-Tetramethyl-1H,4H-3a,6a-propano-pentalene (83043-52-1) → (±)-modhephene (76739-64-5)

Guidance literature:

With hydrogen; platinum(IV) oxide;

DOI:10.1021/ja00385a051

Reference yield: 84.0%

(3aR,4S,6aS)-1,1,3,4-Tetramethyl-1H-3a,6a-propano-pentalen-5-one (77347-00-3,121469-27-0) → (±)-modhephene (76739-64-5)

Guidance literature:

With potassium carbonate; hydrazine hydrate; In diethylene glycol; 1.) l60 deg C, 2h, 2.) 230 deg C, 2.5 h (distillation), then same temp, 1.5 h;

DOI:10.1016/0040-4020(81)80009-9

upstream raw materials:

dimethyl zinc(II)

4,6-dimethyltricyclo<3.3.3.0>undec-3-en-2-one

(1R*,5S*,6S*)-2,2,6-trimethyl-4-methylidentricyclo[3.3.3.0]undecan

(1S,3aS,6aS)-1,7,9,9-Tetramethyl-tetrahydro-3a,6a-propano-pentalen-8-ol