Technology Process of Methyl-2β,16α,20α-curanoat
There total 7 articles about Methyl-2β,16α,20α-curanoat which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium cyanoborohydride;
In
acetic acid;
at 10 ℃;
for 2h;
Overall yield = 79 %; Overall yield = 442 mg;
Inert atmosphere;
DOI:10.1002/anie.201505198
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / 0.17 h / -10 °C / Inert atmosphere
1.2: 14 h / -10 - 20 °C / Inert atmosphere
2.1: palladium diacetate; triphenylphosphine; triethylamine / 3.5 h / 90 °C / Inert atmosphere
3.1: platinum(IV) oxide; hydrogen / methanol / 24 h / 20 °C / Inert atmosphere
4.1: sodium cyanoborohydride / acetic acid / 2 h / 10 °C / Inert atmosphere
With
platinum(IV) oxide; hydrogen; palladium diacetate; sodium cyanoborohydride; potassium carbonate; triethylamine; triphenylphosphine;
In
methanol; acetic acid; acetonitrile;
2.1: |Heck Reaction;
DOI:10.1002/anie.201505198
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: trifluoroacetic acid / dichloromethane / 13 h / 0 - 20 °C / Inert atmosphere
2.1: potassium carbonate / acetonitrile / 0.17 h / -10 °C / Inert atmosphere
2.2: 14 h / -10 - 20 °C / Inert atmosphere
3.1: palladium diacetate; triphenylphosphine; triethylamine / 3.5 h / 90 °C / Inert atmosphere
4.1: platinum(IV) oxide; hydrogen / methanol / 24 h / 20 °C / Inert atmosphere
5.1: sodium cyanoborohydride / acetic acid / 2 h / 10 °C / Inert atmosphere
With
platinum(IV) oxide; hydrogen; palladium diacetate; sodium cyanoborohydride; potassium carbonate; triethylamine; triphenylphosphine; trifluoroacetic acid;
In
methanol; dichloromethane; acetic acid; acetonitrile;
3.1: |Heck Reaction;
DOI:10.1002/anie.201505198
