(S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine

Base Information

• Chemical Name: (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine
• CAS No.: 127292-64-2
• Molecular Formula: C₁₂H₂₃N*C₂₄H₃₄N₄O₆
• Molecular Weight: 655.878
• Mol file: 127292-64-2.mol

Synonyms:

Chemical Property of (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine

There total 1 articles about (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-alanyl-L-valine (1472-66-8,1999-46-8,3303-45-5,3303-46-6,61427-69-8,99146-59-5) + 2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 4-nitro-phenyl ester (15160-31-3,92608-63-4) + N-cyclohexyl-cyclohexanamine (101-83-7) → (S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine (127292-64-2)

Guidance literature:

Yield given. Multistep reaction; 1.) 1 N NaOH, dioxane, 2.) ether;

DOI:10.1007/BF00597661

Reference yield:

(S)-2-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-3-methyl-butyric acid; compound with dicyclohexyl-amine (127292-64-2) → TrpAlaValGlyHisLeuMetNH2 (55749-98-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 58 percent / 2 N hydrogen chloride / acetic acid

With hydrogenchloride; In acetic acid;

DOI:10.1007/BF00597661

upstream raw materials:

L-alanyl-L-valine

2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 4-nitro-phenyl ester

N-cyclohexyl-cyclohexanamine

Downstream raw materials:

TrpAlaValGlyHisLeuMetNH2