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BOMBESIN (8-14) is a peptide fragment of bombesin, a neuropeptide that functions as a neurotransmitter in the brain and a hormone in the gastrointestinal tract. It is derived from the precursor peptide progastrin-releasing peptide (GRP) and is known to bind to the bombesin receptor, a G protein-coupled receptor involved in various physiological processes. BOMBESIN (8-14) has potential applications in cancer imaging and therapy due to its ability to bind to cancer cells that overexpress bombesin receptors, making it a potential targeting agent for diagnostic or therapeutic purposes. It is also being studied for its role in regulating appetite and energy balance.

55749-98-9

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55749-98-9 Usage

Uses

Used in Cancer Imaging and Therapy:
BOMBESIN (8-14) is used as a targeting agent for cancer imaging and therapy, as it binds to certain types of cancer cells that overexpress bombesin receptors. This property allows for the development of diagnostic tools and therapeutic agents that can specifically target these cancer cells, potentially improving the accuracy and effectiveness of cancer treatments.
Used in Appetite and Energy Balance Regulation:
BOMBESIN (8-14) is used as a regulatory agent in the study of appetite and energy balance. Its role in the regulation of these processes is being investigated, with the potential to contribute to the development of treatments for obesity and related metabolic disorders. By understanding the mechanisms through which BOMBESIN (8-14) influences food intake and body weight regulation, researchers can explore new approaches to managing these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 55749-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,4 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 55749-98:
(7*5)+(6*5)+(5*7)+(4*4)+(3*9)+(2*9)+(1*8)=169
169 % 10 = 9
So 55749-98-9 is a valid CAS Registry Number.

55749-98-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[2-[[2-[[2-[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]-3-methylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-N-(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)-4-methylpentanamide

1.2 Other means of identification

Product number -
Other names Trp-Ala-Val-Gly-His-Leu-Met-NH2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55749-98-9 SDS

55749-98-9Downstream Products

55749-98-9Relevant academic research and scientific papers

SYNTHESIS OF C-TERMINAL FRAGMENTS OF BOMBESIN AND THEIR ANALOGUES

Kuranova, I. L.,Churkina, S. I.,Dyudmirova, V. L.,Filonova, E. B.,Ibatullin, F. M.,et al.

, p. 475 - 484 (2007/10/02)

With the aim of structural-functional studies in the bombesin series, a number of bombesin fragments and analogues have been synthesized.The synthesis was performed by the carbodiimide method and by the activated-ester method.Fragments with the sequences

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