N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid

Base Information

• Chemical Name: N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid
• CAS No.: 106885-35-2
• Molecular Formula: C₂₅H₃₂N₄O₆
• Molecular Weight: 484.552
• Mol file: 106885-35-2.mol

Synonyms:

Chemical Property of N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid

There total 1 articles about N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-valine methylester hydrochloride (6306-52-1) + N-Benzyloxycarbonyl-L-glutaminsaeure-γ-phenylhydrazid → N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid (106885-35-2)

Guidance literature:

Multistep reaction; (i) 2-ethyl-5-(3-sulfo-phenyl)-isoxazolium betaine, Et₃N, MeCN, (ii) /BRN= 3594960/, Et₃N;

DOI:10.1021/jo01037a043

Reference yield:

N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid (106885-35-2) → L-glutamyl-L-valine (5879-06-1)

Guidance literature:

Multi-step reaction with 3 steps

1: MnO₂, aq. AcOH / Ambient temperature

2: aq. NaOH / Ambient temperature

3: H₂ / Pd-C / methanol; H₂O / 1520 Torr

With manganese(IV) oxide; sodium hydroxide; hydrogen; acetic acid; palladium on activated charcoal; In methanol; water;

DOI:10.1021/jo01037a043

Reference yield:

N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester-γ-phenylhydrazid (106885-35-2) → N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester (4579-28-6)

Guidance literature:

With manganese(IV) oxide; acetic acid; Ambient temperature;

DOI:10.1021/jo01037a043

upstream raw materials:

L-valine methylester hydrochloride

Downstream raw materials:

N-Benzyloxycarbonyl-α-L-glutamyl-L-valin-methylester

L-glutamyl-L-valine