4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone

Base Information

• Chemical Name: 4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone
• CAS No.: 1152113-38-6
• Molecular Formula: C₁₀H₁₄ClFN₆
• Molecular Weight: 272.713
• Mol file: 1152113-38-6.mol

Synonyms:

Chemical Property of 4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone

There total 1 articles about 4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,4S)-2-Methyl-2,5-diazabicyclo<2.2.1>heptane Dihydrobromide (114086-15-6,125224-62-6,125224-64-8) + 2,4,6-trichloro-5-fluoropyrimidine (6693-08-9) → 4-chloro-5-fluoro-6-((1S,4S)-5-methyl-2,5-diazazbicyclo[2.2.1]hept-2-yl)-2(1H)-pyrimidinone hydrazone (1152113-38-6) + (1S,4S)-2-(2-chloro-5-fluoro-6-hydrazino-4-pyrimidinyl)-5-methyl-2,5-diazazbicyclo[2.2.1]heptane (1152110-12-7)

Guidance literature:

(1S,4S)-2-Methyl-2,5-diazabicyclo<2.2.1>heptane Dihydrobromide; 2,4,6-trichloro-5-fluoropyrimidine; With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃; for 2.5h;

With hydrazine; In dimethyl sulfoxide; at 20 ℃;

upstream raw materials:

(1S,4S)-2-Methyl-2,5-diazabicyclo<2.2.1>heptane Dihydrobromide

2,4,6-trichloro-5-fluoropyrimidine