3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine

Base Information

Chemical Name:3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine
CAS No.:945971-04-0
Molecular Formula:C₇H₇F₃N₂
Molecular Weight:176.141
Hs Code.:
Mol file:945971-04-0.mol

Synonyms:

Suppliers and Price of 3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-methyl-5-(trifluoromethyl)-2-Pyridinamine 97.00%
5G
$ 3300.00

AccelPharmtech
3-methyl-5-(trifluoromethyl)-2-Pyridinamine 97.00%
1G
$ 1950.00

Total 7 raw suppliers

Chemical Property of 3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine

Chemical Property:

Boiling Point:221.6±40.0 °C(Predicted)
PKA:4.86±0.49(Predicted)
Density:1.307±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

3-methyl-5-(trifluoromethyl)-2-Pyridinamine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 3-Methyl-5-(trifluoromethyl)-2-pyridinamine is a reactant in the preparation of fluazaindolizine analogs and structure activity in control of plant parasitic nematodes.

Technology Process of 3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine

There total 1 articles about 3-Methyl-5-(trifluoroMethyl)-2-pyridinaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 823-96-1
Trimethylboroxine

: 79456-26-1
2-amino-3-chloro-5-(trifluoromethyl)pyridine

: 945971-04-0
3-methyl-5-(trifluoromethyl)pyridin-2-amine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In 1,2-dimethoxyethane; at 130 ℃; Inert atmosphere; Microwave irradiation;

Reference yield:

: 945971-04-0
3-methyl-5-(trifluoromethyl)pyridin-2-amine

: 69812-51-7
4-chlorosulfonyl-benzoic acid methyl ester

: C₁₅H₁₃F₃N₂O₄S

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/j.bmcl.2014.10.074

Reference yield:

: 945971-04-0
3-methyl-5-(trifluoromethyl)pyridin-2-amine

: 1254206-37-5
4-(N-benzyl-N-(3-methyl-5-(trifluoromethyl)pyridin-2-yl)sulfamoyl)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2: caesium carbonate; sodium iodide / N,N-dimethyl-formamide / 80 °C

3: water; sodium hydroxide / tetrahydrofuran / 50 °C

With water; sodium hydride; caesium carbonate; sodium iodide; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.10.074