propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate

Base Information

Chemical Name:propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate
CAS No.:78816-60-1
Molecular Formula:C₂₁H₂₃ClN₂O₃
Molecular Weight:386.878
Hs Code.:
DSSTox Substance ID:DTXSID901110980
Mol file:78816-60-1.mol

Synonyms:isopropyl 5-(3-chloropropanoyl)-10,11-dihydro-5H-dibenzo[b,f]azepin-3-ylcarbamate;SCHEMBL19225001;DTXSID901110980;STL307795;AKOS003669956;propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate;AI-020/12028004;propan-2-yl [5-(3-chloropropanoyl)-10,11-dihydro-5H-dibenzo[b,f]azepin-3-yl]carbamate;78816-60-1;Carbamic acid, N-[5-(3-chloro-1-oxopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]-, 1-methylethyl ester

Suppliers and Price of propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:386.1397203
Heavy Atom Count:27
Complexity:528

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC(=O)NC1=CC2=C(CCC3=CC=CC=C3N2C(=O)CCCl)C=C1

Technology Process of propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate

There total 6 articles about propan-2-yl N-[11-(3-chloropropanoyl)-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78816-59-8
3-Carbisopropoxyamino-10,11-dihydro-5H-dibenzazepin

: 625-36-5
2-chloropropionyl chloride

: 78816-60-1
3-Carbisopropoxyamino-5-β-chlorpropionyl-iminodibenzyl

Guidance literature:: In toluene; for 4h; Yield given; Heating;

Reference yield:

: 10464-35-4
3-amino-10,11-dihydro-5H-dibenzazepine

: 78816-60-1
3-Carbisopropoxyamino-5-β-chlorpropionyl-iminodibenzyl

Guidance literature:: Multi-step reaction with 2 steps

1: Na₂CO₃ / acetone; H₂O / 1.5 h

2: toluene / 4 h / Heating

With sodium carbonate; In water; acetone; toluene;

Reference yield:

: 84803-67-8
3-amino-5-acetyl-10,11-dihydro-5H-dibenzazepine

: 78816-60-1
3-Carbisopropoxyamino-5-β-chlorpropionyl-iminodibenzyl

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; acetic acid / water / Reflux

2.1: ethanol / 0.33 h / 0 °C

2.2: 1 h / 15 - 25 °C

3.1: toluene / 3 h / 100 °C

With hydrogenchloride; acetic acid; In ethanol; water; toluene;