3-Methylenetetrahydrofuran

Base Information

• Chemical Name: 3-Methylenetetrahydrofuran
• CAS No.: 75394-90-0
• Molecular Formula: C₅H₈O
• Molecular Weight: 84.1179
• European Community (EC) Number: 892-162-1
• Nikkaji Number: J1.986.915F
• Mol file: 75394-90-0.mol

Synonyms:3-Methylenetetrahydrofuran;75394-90-0;3-methylideneoxolane;3-methylideneoxolane';AMY6014;AKOS013990302;EN300-3425442

Chemical Property of 3-Methylenetetrahydrofuran

Chemical Property:

• Boiling Point: 92.8±29.0 °C(Predicted)
• Density: 0.89±0.1 g/cm3(Predicted)
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 84.057514874
• Heavy Atom Count: 6
• Complexity: 66.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=C1CCOC1

Technology Process of 3-Methylenetetrahydrofuran

There total 2 articles about 3-Methylenetetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrahydrofuran-3-one (22929-52-8) + Methyltriphenylphosphonium bromide (1779-49-3) → 3-methylene tetrahydrofuran (75394-90-0)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h;

tetrahydrofuran-3-one; In tetrahydrofuran;

Reference yield:

C10H13NOSe (1224431-87-1) → PySeOH (428876-71-5) + 3-methylene tetrahydrofuran (75394-90-0)

Guidance literature:

C₁₀H₁₃NOSe; With Dess-Martin periodane; In dichloromethane; at 20 ℃;

With water; sodium carbonate; at 20 ℃;

DOI:10.1016/j.tetlet.2010.02.002

upstream raw materials:

C₁₀H₁₃NOSe

tetrahydrofuran-3-one

Methyltriphenylphosphonium bromide

Refernces

• 1、 Andreou, Thanos,Burés, Jordi,Vilarrasa, Jaume. "Reaction of Dess-Martin periodinane with 2-(alkylselenyl)pyridines. Dehydration of primary alcohols under extraordinarily mild conditions". scheme or table. p. 1863 - 1866. Retrieved 2010/09/07.