2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid

Base Information

• Chemical Name: 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid
• CAS No.: 121617-84-3
• Molecular Formula: C₁₀H₆ClF₉O
• Molecular Weight: 348.596
• Mol file: 121617-84-3.mol

Synonyms:

Chemical Property of 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid

There total 6 articles about 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-trifluoromethyl-2-butenoic acid ethyl ester (691-77-0) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid (121617-84-3)

Guidance literature:

Multi-step reaction with 5 steps

1: acetonitrile / 1.) 16 h, room temperature; 2.) 24 h, 40 deg C; 3.) 4 h, 60 deg C

3: 85 percent / PPh₃ / CH₂Cl₂ / 1.) -60 deg C, 36 h; 2.) -60 deg C up to room temperature, 10 - 12 h

4: 67 percent / KOH / ethanol; H₂O / 0.5 h / Ambient temperature

5: thionyl chloride / 3 h / Heating

With potassium hydroxide; thionyl chloride; triphenylphosphine; In ethanol; dichloromethane; water; acetonitrile;

Reference yield:

2-Methyl-2-trifluormethyl-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-ethylester (121617-80-9) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid (121617-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / KOH / ethanol; H₂O / 0.5 h / Ambient temperature

2: thionyl chloride / 3 h / Heating

With potassium hydroxide; thionyl chloride; In ethanol; water;

Reference yield:

cis-Trifluorcaronaldehydsaeure-ethylester (121617-79-6) → 2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeurechlorid (121617-84-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / PPh₃ / CH₂Cl₂ / 1.) -60 deg C, 36 h; 2.) -60 deg C up to room temperature, 10 - 12 h

2: 67 percent / KOH / ethanol; H₂O / 0.5 h / Ambient temperature

3: thionyl chloride / 3 h / Heating

With potassium hydroxide; thionyl chloride; triphenylphosphine; In ethanol; dichloromethane; water;

upstream raw materials:

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure

(E)-3-trifluoromethyl-2-butenoic acid ethyl ester

2-Methyl-2-trifluormethyl-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-ethylester

cis-Trifluorcaronaldehydsaeure-ethylester

Downstream raw materials:

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester

2-Methyl-2-(trifluormethyl)-3-<3,3,3-trifluor-2-(trifluormethyl)-1-propenyl>cyclopropancarbonsaeure-(α-cyan-3-phenoxybenzyl)ester

Refernces