Technology Process of 3-(propan-2-yl)[1]benzofuro[3,2-g]cinnolin-4-amine
There total 5 articles about 3-(propan-2-yl)[1]benzofuro[3,2-g]cinnolin-4-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2 / Raney Ni / 80 °C / 22800 Torr
2: NaNO2, 1 N HCl / H2O / 1 h / Ambient temperature
3: 60 percent / sodium acetate / aq. ethanol / 3 h / 0 °C
4: 60 percent / 40percent NaOH / dioxane; H2O / 1 h / Ambient temperature
5: 60 percent / AlCl3 / toluene / 3 h / Heating
With
hydrogenchloride; sodium hydroxide; aluminium trichloride; hydrogen; sodium acetate; sodium nitrite;
nickel;
In
1,4-dioxane; ethanol; water; toluene;
DOI:10.1002/jhet.5570170607
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaNO2, 1 N HCl / H2O / 1 h / Ambient temperature
2: 60 percent / sodium acetate / aq. ethanol / 3 h / 0 °C
3: 60 percent / 40percent NaOH / dioxane; H2O / 1 h / Ambient temperature
4: 60 percent / AlCl3 / toluene / 3 h / Heating
With
hydrogenchloride; sodium hydroxide; aluminium trichloride; sodium acetate; sodium nitrite;
In
1,4-dioxane; ethanol; water; toluene;
DOI:10.1002/jhet.5570170607